Aspectos morfológicos, morfométricos e ultra-estruturais do baço de ratos após o clampeamento total do pedículo hepático

Detalhes bibliográficos
Ano de defesa: 2007
Autor(a) principal: FREITAS, Silvio Henrique de lattes
Orientador(a): EVÊNCIO NETO, Joaquim
Banca de defesa: SIMÕES, Manuel de Jesus, SILVA, Alessandro César Jacinto da, CAMARGO, Lázaro Manoel de, EVÊNCIO, Liriane Baratella
Tipo de documento: Tese
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal Rural de Pernambuco
Programa de Pós-Graduação: Programa de Pós-Graduação em Ciência Veterinária
Departamento: Departamento de Medicina Veterinária
País: Brasil
Palavras-chave em Português:
Palavras-chave em Inglês:
Rat
Área do conhecimento CNPq:
Link de acesso: http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/5843
Resumo: One of the complications of hepatic pedicle total clamping is the splanchnic congestion and consequently a splenic congestion. The aim of this study was to evaluate the macro and microscopic alterations that occurred in the spleen during an ischemia produced by the hepatic pedicle total clamping. Fourthy male rats were divided in four groups of ten animals each. The control group (C) was not submitted to ischemia and the experimental groups (E1, E2 and E3) were submitted to the clamping during 10, 20 and 30 minutes, respectively. After these periods, spleen fragments were collected and histological analyzed by the eosin-hematoxilin and ferric ferrocyanide staining technique. Based on the results it is possible to conclude that 10 minutes of hepatic pedicle total clamping is sufficient to show signs of splenic congestion and 20 and 30 minutes promote intense red bood cels digestion by the macrophages with the presence of iron granules (hemosiderin) at the splenic parenchyma.