Detalhes bibliográficos
| Ano de defesa: |
2008 |
| Autor(a) principal: |
SILVA, Roberto Rômulo Ferreira da
 |
| Orientador(a): |
EVÊNCIO NETO, Joaquim |
| Banca de defesa: |
MAIORINO, Fernando Corleto,
ABREU, Silvio Romero de Oliveira,
ALMEIDA, Edivaldo Lopes de |
| Tipo de documento: |
Dissertação
|
| Tipo de acesso: |
Acesso aberto |
| Idioma: |
por |
| Instituição de defesa: |
Universidade Federal Rural de Pernambuco
|
| Programa de Pós-Graduação: |
Programa de Pós-Graduação em Ciência Veterinária
|
| Departamento: |
Departamento de Medicina Veterinária
|
| País: |
Brasil
|
| Palavras-chave em Português: |
|
| Área do conhecimento CNPq: |
|
| Link de acesso: |
http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/5851
|
Resumo: |
The aim of this study was to evaluate the effects of 0.5% sodium hypochlorite (NaClO) in the healing of open wounds in the skin, induced experimentally in 24 rats(Rattus norvegicus albinus), 4 months of age, male, weighing approximately 250g. Two surgically injuries were performed in the right and left lateral sides of the chest. The wound located into the right antimere was treated with 0.5% NaClO and the contralateral wound received 0.9 %. sodium chloride (NaCl) solution. To measure the wounds contraction, morphometric analysis were accomplished at the beginning of the experiment (time zero) and post-surgery at times 3, 7 and 14 days. The data were statistically analyzed by the Uniformity KS test, and the groups were compared by ANOVA and TUKEY tests. The histopathological analysis of the post-surgical injuries’ fragment showed that the wounds treated with 0.5% NaClO presented greater contraction at day 14 compared to those treated with 0.9% NaCl. In addition an expressive decrease in the neovascularization at day 14 and a greater tendency to the organization of fibrous tissue at day 21 were observed in the lesions treated with 0.5 % NaClO. However, no statistical difference (p ≤ 0.05) was observed for each time trial in both treatments. Nevertheless, it was observed that 0.5% NaClO caused greater reduction in the treated wounds and therefore this antiseptic could be suggested as an alternate treatment for open wounds in the Veterinary Medicine. |
