Estudo histopatológico da implantação de nervo periférico no osso

Detalhes bibliográficos
Ano de defesa: 2015
Autor(a) principal: Varanda, Denis [UNESP]
Orientador(a): Não Informado pela instituição
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Estadual Paulista (Unesp)
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
Link de acesso: http://hdl.handle.net/11449/132002
http://www.athena.biblioteca.unesp.br/exlibris/bd/cathedra/05-10-2015/000847943.pdf
Resumo: Introduction - There are several surgical techniques for treatment of painful amputation neuroma. However no consensus has already been reached on the most effective treatment. Burying the neuroma or the nerve in the bone is one of the surgeries which provides good clinical findings. However, there is no deep knowledge of what happens to the nerve or buried neuroma in the bone. Objectives - The objectives of this study were to develop an experimental model of this surgical technique and to morphologically analyze the destiny of the implanted nerve in the bone. Materials and Methods - A total of 24 four rats underwent implantation of the caudal tibial nerve in the distal third of the femur. They were histologically studied in the periods of 1, 3, 6, 13, 24 and 28 weeks by optical microscopy. Conclusion - The analyses of the images showed that implantation of the nerve in the bone triggers an inflammatory response which evolves from the acute phase to the nerve-bone integration with no formation of neuroma