Detalhes bibliográficos
Ano de defesa: |
2014 |
Autor(a) principal: |
Capuano Neto, Fausto [UNESP] |
Orientador(a): |
Não Informado pela instituição |
Banca de defesa: |
Não Informado pela instituição |
Tipo de documento: |
Dissertação
|
Tipo de acesso: |
Acesso aberto |
Idioma: |
por |
Instituição de defesa: |
Universidade Estadual Paulista (Unesp)
|
Programa de Pós-Graduação: |
Não Informado pela instituição
|
Departamento: |
Não Informado pela instituição
|
País: |
Não Informado pela instituição
|
Palavras-chave em Português: |
|
Link de acesso: |
http://hdl.handle.net/11449/113894
|
Resumo: |
The aim of this paper is to evaluate the osteoinduction ability of fibrin sealant derived from snake venom (SFPS) when combined with Bio-Oss ® (BHA) and compare SFPS and collagen membrane in repairing the sinus membranes perforations during sinus lift. In group 1, 16 rabbits underwent a lesion of 4 mm in the sinus membrane on both sides and then treated with sealant or collagen membrane. In group 2, 16 rabbits received BHA and BHA + SFPS on each side of the sinus. The group 1 animals were euthanized at 3, 7, 14 and 30 days and Group 2 at 7, 14, 30 and 60 days. The evaluation was made by optical microscopy and histomorphometric analysis. In group 1 both techniques were effective and no fibrosis, defective in the ciliated epithelium or intense inflammation were observed in any case. In group 2, the SFPS created a network that prevented the penetration of cells, being completely reabsorbed in 30 days, delaying the ossification. The resorption of fibrin promoted an intense inflammatory infiltrate that dissipated with time and did not prevent the ossification. Fibrin sealant has proven effective in the correction of sinus membrane lesions, but delayed bone formation, when combined with Bio-Oss® |