Análise do exercício físico e eletroestimulção do músculo tibial cranial após neurorrafia término-lateral do nervo fibular em ratos

• Ano de defesa: 2015
• Autor(a) principal: Rosa, Vívian Cristina [UNESP]
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Estadual Paulista (Unesp)
• Palavras-chave em Português: Cirurgia; Exercícios físicos; Nervos cranianos; Estimulos eletricos; Rato como animal de laboratorio; Surgery
• Link de acesso: http://hdl.handle.net/11449/132683; http://www.athena.biblioteca.unesp.br/exlibris/bd/cathedra/18-12-2015/000854927.pdf

Lesions of peripheral nerves can be extremely disabling. In this context, microsurgery has presented a major role in the treatment of patients. However, even with all technical refinement achieved by microsurgery, full motor recovery has not been ensured yet. This can be explained by muscle degeneration, atrophy and functional losses generated by denervation. In the clinical setting, some physiotherapy resources have been suggested in order to minimize losses due to denervation. Among these resources, electrical stimulation and exercise are the main options. The use of electrical stimulation is justified because it is able to minimize the atrophy during denervation. Differently, the application of exercise is justified to stimulate the production of neurotrophic factors, a fact that could enhance axonal regeneration and, next, to promote better reinnervation. However, to both electrical stimulation and exercise there are some controversies regarding the parameters used. The aim of this study was to analyze the efficiency of electrical stimulation, swimming exercise and the association between these two actions, in nerve regeneration after fibular nerve end-to-side neurorraphy. For the experiment, the animals were divided into two control groups GC and GD and 4 experimental groups GNTL, GNTL + EE, GNTL + N and GNTL + EE + N. The animals of the experimental groups underwent experimental surgery of end-to-side neurorraphy and in three post surgical groups the protocols of electrostimulation, swimming exercise and the association between electrostimulation and swimming were used. The results demonstrated that electrical stimulation, physical exercise and the association of the treatments showed superior results compared to GNTL group and the group GNTL + EE + N was superior to treatment isolated groups in nerve and muscle regeneration