Avaliação da resposta tecidual e capacidade de mineralização de cimentos que contém compostos biocerâmicos, resinosos e com hidróxido de cálcio

• Ano de defesa: 2015
• Autor(a) principal: Bueno, Carlos Roberto Emerenciano [UNESP]
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Estadual Paulista (Unesp)
• Palavras-chave em Português: Teste de materiais; Inflamação; Cimentos dentarios; Hidróxido de cálcio; Dental cements
• Link de acesso: http://hdl.handle.net/11449/127852; http://www.athena.biblioteca.unesp.br/exlibris/bd/cathedra/04-09-2015/000847813.pdf

The cleaning and shaping of root canals is essential to achieve biological and mechanical goals in the endodontic treatment, providing the appropriate conical shape for subsequent obturation. The optimal obturation is a combination of a sealer with a central core, usually gutta percha, spreading and filling possible gaps. Once there is a direct contact with periapical tissue, the sealer should be biocompatible and, if possible, stimulate mineralization to perform an apical sealing. In order to evaluate in vivo biological response and tissue mineralization capacity of the endodontic sealers Smartpaste Bio® Sealapex® and Acroseal®, subcutaneous implants in 40 Wistar rats were performed. Analisys were at 7, 15, 30 and 60 days experimental periods (10 animals for each time period). Each animal received four implants, three polyethylene tubes with the sealers in test and one empty tube as control. After each post-operative period animals were euthanized and the polyethylene tubes, along with surrounding tissue were removed and fixed. In order to histologically analysis fibrous capsule thickness, inflammatory infiltrate and mineralization, the pieces were included in historesin and stained in HE, Von Kossa or remained without staining for observation under polarized light. The results were statistically analyzed by Kruskal-Wallis and Dunn (p<0,05). Results: All sealers promoted moderate inflammatory reaction at initial periods. Smartpaste Bio® presented the lowest inflammatory reaction at 15 days period (p<0.05). Sealapex® induced higher mineralization, followed by Smartpaste Bio®. Acroseal® showed no mineralization areas. Conclusion: At the end of the experiment, all tested sealers presented biocompatibility. With exception of Acroseal, all induced biomineralization.