Influência da diabetes mellitus na resposta tecidual e na capacidade de mineralização dos cimentos Sealapex, MTA Angelus e MTA Fillapex

• Ano de defesa: 2013
• Autor(a) principal: Queiroz, Índia Olinta de Azevedo [UNESP]
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Estadual Paulista (Unesp)
• Palavras-chave em Português: Diabetes; Cimentos dentarios; Endodontia; Endodontics
• Link de acesso: http://hdl.handle.net/11449/123832; http://www.athena.biblioteca.unesp.br/exlibris/bd/cathedra/25-05-2015/000831085.pdf

Objective: The aim of this study was to evaluate the influence of diabetes mellitus on tissue response and mineralization ability of Sealapex® MTA Angelus® and MTA Fillapex® sealers. Methods: Twenty-four Wistar rats were divided into two groups: diabetics induced by Alloxan and non-diabetics. The materials were placed in the polyethylene tubes and implanted into dorsal connective tissue of rats for 7 and 30 days. Six animals from each group received injection with calcein on day 7, alizarin on day 14 and oxytretacycline hydrochloride on day 21. The animals were killed after 7 and 30 days and the specimens were prepared for histologic analysis with hematoxylin and eosin, Von Kossa technique, and not stained for polarized light or fluorescence. Results: On 7 days, it was observed similar inflammatory reactions among all groups characterized by a moderate inflammatory response and on 30 days, it was found a mild inflammatory response. Both materials groups exhibited positive structures on Von Kossa and Polarized light analysis either on 7 and 30 days. Sealapex® and MTA Fillapex® showed more fluorescence intensity than MTA Angelus® (p<0.05) for all fluorochromes in non-diabetic group and for alizarin and oxytretacycline in diabetic group. It was not observed difference between Sealapex® and MTA Fillapex® for all fluorochromes independently on the diabetic condition. Fluorescence intensity was not changed with any material in diabetic rats. Conclusion: It was concluded that diabetes mellitus did not influence the tissue response or mineralization stimulated by Sealapex® or MTA Angelus® or MTA Fillapex®