Fatores de risco para injúria renal aguda em pacientes submetidos à hepatectomia parcial

Detalhes bibliográficos
Ano de defesa: 2017
Autor(a) principal: Bredt, Luis César lattes
Orientador(a): Peres, Luis Alberto Batista lattes
Banca de defesa: Peres , Luis Alberto Batista lattes, Araujo , Allan Cezar Faria lattes, Delfino, Vinicius Daher Alvares lattes
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Estadual do Oeste do Paraná
Cascavel
Programa de Pós-Graduação: Programa de Pós-Graduação em Biociências e Saúde
Departamento: Centro de Ciências Biológicas e da Saúde
País: Brasil
Palavras-chave em Português:
Palavras-chave em Inglês:
Área do conhecimento CNPq:
Link de acesso: http://tede.unioeste.br/handle/tede/3681
Resumo: This research aims to identify risk factors for the occurrence of acute kidney injury (AKI) in the postoperative period of partial hepatectomies. Methods: Retrospective analysis of 446 consecutive resections in 405 patients, analyzing clinical characteristics, preoperative laboratory data, intraoperative data, and postoperative laboratory data and clinical evolution. Adopting the International Club of Ascites (ICA) criteria for the definition of AKI, potential predictors of AKI by logistic regression were identified. Results: Of the total 446 partial liver resections, postoperative AKI occurred in 80 cases (17.9%). Identified predictors of AKI were: non-dialytic chronic kidney injury (CKI), biliary obstruction, the Model for End-Stage Liver Disease (MELD) score, the extent of hepatic resection, the occurrence of intraoperative hemodynamic instability, post-hepatectomy haemorrhage (PHH), and postoperative sepsis. Conclusion: The MELD score, the presence of non-dialytic CKI and biliary obstruction in the preoperative period, and perioperative hemodynamics instability, bleeding, and sepsis are risk factors for the occurrence of AKI in patients that underwent partial hepatectomy.