Reparo ósseo utilizando enxerto de matriz orgânica bovina: análise histológica em calvária de coelhos

Detalhes bibliográficos
Ano de defesa: 2007
Autor(a) principal: Silveira, Rubens Jorge
Orientador(a): Não Informado pela instituição
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de Uberlândia
BR
Programa de Pós-graduação em Odontologia
Ciências da Saúde
UFU
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
Link de acesso: https://repositorio.ufu.br/handle/123456789/17050
Resumo: Xenogenic graft of bone origin has been used to favor bone regeneration and to reduce autogenous bone needs. The purpose of this study was to evaluate the bone repair induced by particulate bovine organic bone grafted in rabbit calvaria. Two standardized bone defects were prepared in both parietal of 20 adult rabbits. The defects were filled by clot, autograft, medular organic bovine bone or cortical organic bovine bone. Thirty days following surgery animals were killed; the calvaria were removed, fixed in formol, demineralized in EDTA and embedded in paraffin. Histological sections were stained in HE or Mallory Trichrome and analyzed by light microscope. On group filled with clot only the half of the defect was repaired by new bone tissue, which was formed from lesion border, central area presented cellular connective tissue. In defects filled with autograft almost all defect was repaired by bone tissue. Defects grafted with medular or cortical bovine bone exhibited near ¼ of defect filled by bone tissue, formed from border, with central area occupied by fibrous connective tissue. Almost all xenogenic grafts were reabsorbed, remaining few fragments that were associated to foreign body giant cell reaction and few showing bone neoformation around. Therefore, the graft of organic bovine bone, medular or cortical, used in an isolated way, didn't favor the process of bone repair.