Efeitos da suplementação com nitrato de sódio sobre biomarcadores salivares de intensidade de exercício e estresse oxidativo, e variáveis hemodinâmicas de homens fisicamente ativos

• Ano de defesa: 2015
• Autor(a) principal: Simões, Eduardo Felipe Menezes
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Uberlândia; Brasil; Programa de Pós-graduação em Genética e Bioquímica
• Palavras-chave em Português: Bioquímica; Stress oxidativo; Saliva; Exercícios físicos; Suplementação com nitrato; Óxido nítrico; Pressão arterial; Nitrate supplementation; Nitric oxide; Oxidative stress; Blood Pressure; Exercise; CNPQ::CIENCIAS BIOLOGICAS::GENETICA
• Link de acesso: https://repositorio.ufu.br/handle/123456789/17860; https://doi.org/10.14393/ufu.di.2015.364

This study evaluated the nitrate supplementation effects on exercise intensity and oxidative stress markers and hemodynamic variables in physically active male subjects. Fourteen subjects were submitted to four tests with an interval of five days between them. The nitrate (NO group) and placebo supplementation (PL group) were acute (AC) and during the following five days (FD). Saliva was collected at basal (0’), sixty minutes after supplementation (60’), immediately after exercise (90’), fifteen, thirty and sixty minutes after test (105’, 120’ and 150’). NO group had higher concentrations of nitrite in both treatments when compared with PL group. Furthermore, the area under the curve of NO group shows that the uric acid and FRAP concentrations had a higher profile and a lower systolic blood pressure profile in FD. However, there was no difference between the exercise intensity biomarkers. The results suggest that nitrate supplementation indirectly acted as an antioxidant and modulated the systolic blood pressure, positive characteristics for vascular health.