Efeitos hemodinâmicos da pressão positiva contínua nas vias aéreas avaliados pelo ecodopplercardiograma
Ano de defesa: | 2015 |
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Autor(a) principal: | |
Orientador(a): | |
Banca de defesa: | |
Tipo de documento: | Dissertação |
Tipo de acesso: | Acesso aberto |
Idioma: | por |
Instituição de defesa: |
Universidade Federal de Uberlândia
BR Programa de Pós-graduação em Ciências da Saúde Ciências da Saúde UFU |
Programa de Pós-Graduação: |
Não Informado pela instituição
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Departamento: |
Não Informado pela instituição
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País: |
Não Informado pela instituição
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Palavras-chave em Português: | |
Link de acesso: | https://repositorio.ufu.br/handle/123456789/12833 https://doi.org/10.14393/ufu.di.2015.104 |
Resumo: | Although the use of continuous positive airway pressure (CPAP) has increased considerably, there have been few studies of its hemodynamic effects in patients with healthy cardiopulmonary systems. Objective: To evaluate the hemodynamic effects exerted by different levels of continuous positive airway pressure in healthy individuals using Doppler echocardiography. Methods: This study included 19 healthy volunteers. Three levels of continuous positive airway pressure (5, 10 and 15 cm H2O) were randomly applied for 5 minutes each; 5 minutes of rest were allowed between each application. Echocardiographic variables, vital signs and ventilation were each recorded at baseline and following each pressure application. Results: Continuous positive airway pressures of 10 and 15 cm H2O generated a reduction in the pulmonary velocity-time integral (p=0.01), as well as a reduction in right atrial area (p=0.00). Both cardiac output and heart rate were significantly decreased with each pressure setting (p=0.00 and p=0.00, respectively), whereas stroke volume and blood pressure did not change significantly. Positive correlations were observed between the mitral, pulmonary and aortic velocity-time integrals and both stroke volume and cardiac output. Conclusion: Continuous positive airway pressures of 10 and 15 cm H2O generated reductions in right ventricular preload without changing either left ventricular preload or left ventricular afterload. There was also a decrease in cardiac output due to a reduction in heart rate. A strong correlation was observed between the mitral velocity-time integral and both stroke volume and cardiac output. |