Colonização e infecção por Staphylococcus aureus resistente (MRSA) e suscetível (MSSA) à Meticilina no berçário de alto risco do Hospital de Clínicas da Universidade Federal de Uberlândia

• Ano de defesa: 2003
• Autor(a) principal: Silva, Helisângela de Almeida
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Uberlândia; Brasil; Programa de Pós-graduação em Imunologia e Parasitologia Aplicadas
• Palavras-chave em Português: Estudo de incidência de infecção; Staphylococcus aureus; CNPQ::CIENCIAS BIOLOGICAS::IMUNOLOGIA
• Link de acesso: https://repositorio.ufu.br/handle/123456789/27221; http://dx.doi.org/10.14393/ufu.di.2003.25

It was accomplished an infection incidence and colonization prevalence study for Staphylococcus aureus in the High Risk Nursery of the Clinics Hospital, Federal University of Uberlândia. Staphylococcal infections were observed by analyzing medicai records in HICS (Hospital Infection Control Service) and the HRN. Additionally four inquiries of punctual colonization prevalence were accomplished for 8. aureus, from january/2000 to december/2002. The frequency of neonates colonized by S. aureus was 48.95%. MSSA was more prevalent (57.15%) than MRSA (42.85%). MRSA was more prevalent in the second inquiry (78,94%). Intestine was the most usual site colonization by S. aureus (34,87%); MRSA was the most prevalent phenotype (63,90%). Statistically significant difference was observed in the different sections of HRN, especially between Extern Nursery (EN) and UTI by analyzing neonates colonized by S. aureus. In relation to MRSA it was more frequently observed in EN than in Inter. Antibiotic use was statistically significant in BE than Inter, as well. Risk factors related to acquisition of MRSA were: low weight and antibiotic use. In relation to colonization by S. aureus, hospital stay was the only significant variable observed. The incidence of infections by 5. aureus in the last three years was of 3.62% (159 cases). Nine of them (5.66%) were associated to MRSA and 150 (94.34%) to MSSA. Staphylococcal infections were considered as invasive (sepsis) and non-invasive (conjunctivitis, cutaneous), corresponding to 31.44% and 68.56%, respectively. MRSA phenotype presence in infection was low when compared with methicillin-susceptible samples although S.aureus, MRSA and MSSA colonization rates had been high.