Uso de cetoanálogos para redução da amonemia em ratos submetidos a exercícios físicos

• Ano de defesa: 2010
• Autor(a) principal: Almeida, Rosemeire Dantas de
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Uberlândia; BR; Programa de Pós-graduação em Genética e Bioquímica; Ciências Biológicas; UFU
• Palavras-chave em Português: Cetoácidos; Exercícios físicos - Aspectos fisiológicos; Amônia; Exercício; Ammonia; Exercise; Ketoacids; CNPQ::CIENCIAS BIOLOGICAS::GENETICA
• Link de acesso: https://repositorio.ufu.br/handle/123456789/15718

Concentration of ammonia in blood increases during endurance exercise and can be toxic for muscle cells and brain metabolism, potentially leading to both peripheral and central fatigue. Intense exercise can promote failure in replace ATP leading to greater deamination of AMP and consequent increase in blood ammonia. High concentration of ammonia is toxic and harms the performance. Keto acids has been proposed to capture the blood nitrogen compounds. Here we describe the protective effects of acute and chronic keto acids supplementation on nitrogen metabolism and physical performance in male rats submitted to a resistance training protocol. This study investigated the protective effect of supplementation keto analogues against acute nitrogen compounds and physical performance in rats submitted to exercise.