Ferro por via endovenosa versus via oral na recuperação das variáveis hematológicas e qualidade de vida após a abdominoplastia pós-bariátrica: ensaio clínico randomizado

• Ano de defesa: 2017
• Autor(a) principal: Pedroso, Juan Carlos Montano [UNIFESP]
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo (UNIFESP)
• Palavras-chave em Português: Ferro; Anemia; Abdominoplastia; Cirurgia Plástica; Cirurgia bariátrica; Obesidade; Complicações pós-operatórias; Hemoglobinas; Eritropoese
• Link de acesso: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=5015082; http://repositorio.unifesp.br/handle/11600/49925

Background: Patients undergoing post-bariatric abdominoplasty may progress with postoperative anemia. Objective: To evaluate the efficacy of intravenous versus oral iron administration in the recovery of hematological variables after post-bariatric abdominoplasty. Methods: Randomized clinical trial with a 1: 1 allocation ratio involving 56 adult women submitted to post-bariatric abdominoplasty. The study group received 200 mg intravenous iron in the immediate postoperative period and on the first postoperative day. The control group received 100 mg of polymaltosed iron twice daily orally postoperatively for eight weeks. Hematological variables, iron profile, quality of life, complications and adverse effects were evaluated in the preoperative period and in the first, fourth and eighth postoperative weeks. Results: Mean hemoglobin levels in the eighth postoperative week were higher in the study group (12.8g / dL) than in the control group (12.54g / dL, p = 0.009). At the end of follow-up, the control group had a hemoglobin deficit of 0.14 g / dL, while the study group had a gain of 0.57 g / dL (p = 0.002). The incidence of iron deficiency was higher in the control group (81.5%) than in the study group (40.7%, p = 0.002). There were no differences between groups in quality of life and incidence of complications. The study group did not present adverse effects, whereas the control presented predominantly constipation (17.9%) and diarrhea (10.7%). Conclusion: The postoperative administration of iron by intravenous route promoted higher levels of hemoglobin and lower incidence of iron deficiency than the oral route in patients submitted to post-bariatric abdominoplasty.