Evolução do estado nutricional de crianças com tumores do sistema nervoso central durante o primeiro ano do tratamento antineoplásico

• Ano de defesa: 2016
• Autor(a) principal: Tsutsumi, Renata Candido [UNIFESP]
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo (UNIFESP)
• Palavras-chave em Português: Brain tumors; Pediatrics; Nutritional status; Tumores cerebrais; Pediatria; Estado nutricional
• Link de acesso: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=4015900; https://repositorio.unifesp.br/handle/11600/46343

Aim: to evaluate the nutritional status of children with central nervous system tumors during the first year of antineoplastic treatment. Methods: A retrospective cohort study included 30 children aged between 2 and 10 years, of both genders with tumors of the central nervous system treated at GRAACC between 2004 and 2011. Body mass index (BMI), percentage of adequacy triceps skinfold (TSF) and arm muscle circumference (AMC) were evaluated at admission, 6 and 12 months. The frequency of tumors of the central nervous system, were astrocytic 33.3% (10/30), embryonal 40% (12/30) of the sellar region 10% (3/30) and ependymal 16.6% (5/30). Statistical analysis repeated measures analysis of anthropometric variables was performed using the Friedman test. Results: The median ESCOREZ Z BMI at admission - 0.66; 6 months after - 0,59 and 12 months - 0.47 (p = 0.648) and the percentage of adequacy of AMC 98.0% at admission; 6 months after 91.1% and 94.2% after 12 months (p = 0.344) showed that children are eutrophic during the first year of antineoplastic treatment. The median percentage of adequacy of triceps skinfold 83.2% at admission; 6 months after 73.6% and 82.5% after 12 months, showed no significant difference (p = 0.291), indicating mild malnutrition. Among the different diagnoses, the presence of embryonal tumors, caused major negative impact on the evolution of the nutritional status of children, median BMI Z - 1.06; - 1.68 -1.61 after 6 months and after 12 months, as a significant result (p = 0.002). Conclusion: In this group according to the Z BMI analysis parameters and DCT and CMB children show good improvement in nutritional status. The presence of embryonal tumors, has greater negative impact on nutritional status.