Associação entre o Índice Inflamatório da Dieta (IID) e fraturas por baixo impacto em homens e mulheres brasileiros: The Brazilian Osteoporosis Study (BRAZOS)

• Ano de defesa: 2016
• Autor(a) principal: Morimoto, Melissa Aparecida [UNIFESP]
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo (UNIFESP)
• Palavras-chave em Português: Diet; Inflammation; Low-impact fractures; Osteoporosis; Dietary inflammatory index; Dieta; Inflamação; Fraturas de baixo impacto; Osteoporose; Índice inflamatório da dieta
• Link de acesso: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=3889869; https://repositorio.unifesp.br/handle/11600/46647

Adequate nutrition, including intake of dietary calcium and vitamin D, are important to maintain bone health. Evidence suggests that deficiency of some nutrients may contribute to bone loss during aging and exert generalized effects on chronic inflammation. Recently, the Dietary Inflammatory Index (DII) has been developed to assess and evaluate the inflammatory potential of individuals? diets. Aims: To evaluate the DII in a representative sample of men and women aged 40 years or older in Brazil, as well as to verify its association with low-impact fractures. Design: The DII was calculated using the Brazos database, an important epidemiological study carried out in a representative sample of men and women ?40 years old. Research was conducted through in-home interviews administered by a trained team. The Nutrition Database System for Research (NDSR) software program was used to analyze data on the intake of nutrients later employed to calculate the DIIusing Statistical Analysis Software (SAS) and to assess its association with low-impact fractures. Subjects: A total of 2,269 subjects had their DII score calculated using information from 24-hour recall data. Results: Males had lower DII than females (DII=1.12±1.04 versus DII=1.24±0.99, p=0.012). However, men with low impact fractures had significantly higher DII compared to those with no history of fractures (1.24±1.06 versus 1.08±1.04, p=0.048). Women taking statins had lower DII (0.65±1.14 versus 1.26±0.98, p=0.002), indicating greater potential for diet-related anti-inflammatory effects. Conclusion: Our findings suggest that a proinflammatory diet is associated with low-impact fractures in Brazilian adult men.