Consumo alimentar dos portadores de doença hepática gordurosa não alcoólica: comparação entre a presença e ausência de síndrome metabólica e a gravidade da doença

• Ano de defesa: 2011
• Autor(a) principal: Crispim, Fany Govetri Sena [UNIFESP]
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo (UNIFESP)
• Palavras-chave em Português: Consumo Alimentar; Food intake; Insulin resistance; Metabolic syndrome; Resistência à insulina; Síndrome Metabólica; Hepatopatia gordurosa não alcoólica; Non-alcoholic fatty liver disease
• Link de acesso: http://repositorio.unifesp.br/handle/11600/9254

Purpose: To evaluate the dietary intake of subjects with nonalcoholic fatty liver disease (NAFLD) and compare with recommended dietary intake, presence and absence of metabolic syndrome (MS) and disease severity (presence and absence of nonalcoholic steatohepatitis). Methods: We first evaluated 158 patients with a diagnosis of NAFLD by clinical examination, histological analysis, anthropometry (weight, height, BMI, waist circumference) and dietary intake (3 days food record) with analysis of protein, carbohydrates and lipids, including saturated fatty acids (SFA), monounsaturated (MUFA), polyunsaturated (PUFA) and cholesterol, micronutrients (vitamins A, C and E) and total dietary fiber. Of these, 59 presented dietary changes as a result of previous nutritional instruction and were excluded from the analysis. Results: Among the remaining 99 patients, when compared to the recommended dietary intake, we observed a higher intake of cholesterol and saturated fatty acids in 59,5% and 87,8%, respectively, in addition to deficient ingestion of mono- and polyunsaturated fatty acids, fibers, and vitamin E in 98,9 %, 76,7%, 64,6% and 68,6% of these patients, respectively. These findings agree with previous studies involving this population. No significant differences in diet were observed when these patients were divided according to the presence or absence of metabolic syndrome and nonalcoholic steatohepatitis (NASH). Conclusions: In this study, we observed that individuals with NAFLD presented inadequate intake of MUFA, PUFA, vitamin E and fiber and excessive consumption of SFA and cholesterol. However, no significant differences were found in diet of these patients when divided according to presence or absence of MS and NASH.