Método de segmentação de Esclerose Múltipla em imagem de ressonância magnética usando Fuzzy Connectedness, binarização, morfologia matemática e reconstrução 3D

• Ano de defesa: 2020
• Autor(a) principal: Arruda, Andre Luiz Costa De [UNIFESP]
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo (UNIFESP)
• Palavras-chave em Português: Magnetic Resonance Imaging (MRI); Multiple Sclerosis (MS); Segmentation; Fuzzy Connectedness (FC); Reconstruction; Gold Standard (GS); Imagem De Ressonância Magnética (IRM); Esclerose Múltipla (EM); Reconstrução; Ajuste De Contraste; Segmentação
• Link de acesso: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=9751002; https://hdl.handle.net/11600/64687

Magnetic resonance imaging (MRI) is the most used medical modality for diagnosis and monitoring of Multiple Sclerosis (MS). A segmentation process is an important task to quantify lesion and its progression. However, manual segmentation of 3D images is tedious, time consuming and often not reproducible. The state of the art presents results with room for improvements. Consequently, a semiautomatic segmentation process is proposed and described in this study. The method consists on a 3D segmentation semiautomatic process for MS lesions in MRI. It initiates by firstly carried out a preprocessing stage; thus, contrast adjustment is applied to enhance sclerosis regions from other brain information. Secondly, a feature extraction block based on Fuzzy Connectedness is performed so as to isolate sclerosis lesions from other brain regions. Finally, 3D brain reconstruction is executed along with sclerosis to provide a useful 3D information. The robustness of this approach is demonstrated by high correlation between the results and their corresponding Gold Standard. The results were also obtained by computing parameters of accuracy of image segmentation, as well as Overlap Dice. The proposed method reached True Positive of 75.61%, False Positive of 16.37% and Dice of 78.23%. The method is corroborated by its high correlation between specialist and proposed approach outcome; additionally, with the 3D reconstruction of the lesion, a better monitoring of the disease is provided, the specialist can understand the patient's symptoms, thereby increasing the patient's quality of life.