Revisão sistemática sobre dados hematológicos e toxicológicos de doadores de sangue fumantes e não fumantes

• Ano de defesa: 2022
• Autor(a) principal: Cunha, Analuiza Rolim da
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Santa Maria; Brasil; Análises Clínicas e Toxicológicas; UFSM; Programa de Pós-Graduação em Ciências Farmacêuticas; Centro de Ciências da Saúde
• Palavras-chave em Português: Doação de sangue; Tabagismo; Transfusão; Metais pesados; Meta-análise; Interleucinas; Blood donation; Smoking; Interleukins; Transfusion; Heavy metals; Meta-analysis; CNPQ::CIENCIAS DA SAUDE::FARMACIA
• Link de acesso: http://repositorio.ufsm.br/handle/1/24650

Blood donation is essential for public health, in the routine of hospitals and emergency rooms, hundreds of lives are saved every day with the blood donated by the population. Tobacco use is considered by the World Health Organization (WHO) to be the leading cause of preventable death worldwide. Cigarette smoke contains carbon monoxide, with hemoglobin having two hundred times more affinity with it than with oxygen, forming carboxyhemoglobin, which does not transport oxygen. Cigarette smoke increases the content of carbon monoxide in the circulation, as a result, increases the content of carboxyhemoglobin, reducing the amount of oxygen found in the blood. The objective of this study was to determine the profile of smoking and non-smoking blood donors, detecting signs of harmfulness in the blood of smoking donors, through a systematic review of published works carried out in the last 15 years (2006-2021). We found that erythrocyte blood components showed toxic markers, such as carboxyhemoglobin and heavy metals when coming from smoking blood donors, the data corroborate the literature, proving the harmfulness of tobacco