Ciclização intramolecular do 1-benzil-2-alquinilbenzeno promovida por FeCl3 e dicalcogeneto de diorganoíla: síntese dos 9-(organocalcogênio)-5H-benzo[7]anulenos

• Ano de defesa: 2016
• Autor(a) principal: Prochnow, Thaís
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Santa Maria; BR; Química; UFSM; Programa de Pós-Graduação em Química
• Palavras-chave em Português: Carbociclização; Dicalcogeneto de diorganoíla; Alquínos; Carbocyclic; Diorganyl dichalcogenide; Alkines; CNPQ::CIENCIAS EXATAS E DA TERRA::QUIMICA
• Link de acesso: http://repositorio.ufsm.br/handle/1/10614

In the present work, a series of 1-benzyl-2-alkylbenzenes functionalized was subjected to intramolecular cyclization reaction promoted by iron(III) chloride with diorganyl dichalcogenide allowed the synthesis of 9-(organochalcogen)-5H-benzo[7]annulenes whereas the mutual action between diorganyl dichalcogenide and iron(III) chloride in a 0.5:1.0 mole ratio was essential in order to achieve the maximal yields of the products. The cyclization reaction tolerated a variety of functional groups, such as trifluoromethyl, chloro, fluorine and methoxyl, in both 1-benzyl-2-alkynylbenzenes and diorganyl diselenides, giving the seven-membered carbocyclic exclusively via a 7-endo-dig cyclization process, it resulted in a total of 23 samples in 45-77 % yield.