Comparações microbiológicas de indivíduos expostos e não expostos ao crack

• Ano de defesa: 2015
• Autor(a) principal: Casarin, Maísa
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Santa Maria; BR; Odontologia; UFSM; Programa de Pós-Graduação em Ciências Odontológicas
• Palavras-chave em Português: Cocaina/crack; Microrganismos; Periodontite; Reação em cadeia da polimerase em tempo real; Usuários de drogas; Crack cocaine; Drug users; Microorganism; Periodontitis; Real time polymerase chain reaction; CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA
• Link de acesso: http://repositorio.ufsm.br/handle/1/6155

Several risk factors have been shown to be able to adjust the establishment and progression of periodontal disease. There is evidence demonstrating that some illegal drugs like cocaine and heroin can influence the pathogenesis of periodontitis. However, there is little evidence investigating the influence of crack in epidemiology and periodontal profile in periodontitis. The aim of this cross-sectional study with a control group was to compare the count of some periodontal pathogens in individuals exposed to crack the control subjects matched for age, sex and exposure to tobacco. Demographic variables were collected, clinics and subgingival biofilm of 155 subjects (74 exposed to crack / 81 controls). The microbiological outcome was count Aggregatibacter actinomycetemcomitans (Aa), Prevotella intermedia (Pi), Porphyromonas gingivalis (Pg) and Fusobacterium nucleatum (Fn) measured by real time PCR. The results demonstrated that exposure presented in greatest severity insertion loss (P = 0.000), analyzed by McNemar with the exception of marginal gingival bleeding (P = 0.489) and supragingival calculus (P = 0.504), Wilcoxon. No significant differences were observed in the prevalence of counting 106 cells / ml and the total count of bacteria evaluated between groups through Poisson regression with Variance Robusta. In the analysis of subjects who had only the highest bacterial counts (≥ 75%), both in gross nor adjusted analysis, there was a significantly higher prevalence of individuals in the group exposed to crack. It is concluded that the microbiological profile of Aa, Pg, Pi and Fn did not differ between exposed and unexposed to crack.