Efeitos agudos da estimulação elétrica transcutânea nervosa no sistema nervoso autônomo cardiovascular de mulheres com fibromialgia : ensaio clínico aleatorizado

• Ano de defesa: 2019
• Autor(a) principal: Santos, Annanda Oliveira
• Orientador(a): Santana, Josimari Melo de
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Programa de Pós-Graduação: Pós-Graduação em Ciências Fisiológicas
• Palavras-chave em Português: Fibromialgia; Sistema nervoso autônomo; Estimulação elétrica; Sistema cardiovascular; Efeitos adversos
• Palavras-chave em Inglês: Fibromyalgia; Autonomic nervous system; Electrical stimulation; Adverse effects; Cardiovascular system
• Área do conhecimento CNPq: CIENCIAS BIOLOGICAS::FISIOLOGIA
• Link de acesso: http://ri.ufs.br/jspui/handle/riufs/12601

Background: Fibromyalgia (FM) is characterized by the presence of chronic non-inflammatory muscular pain, hyperalgesia, and, allodynia. In addition, systemic disorders such as autonomic imbalances are associated with the syndrome. Seeking alternative treatments for dysautonomia, effects of electric currents have been tested in healthy populations. Literary findings are positive for transcutaneous electrical nerve stimulation (TENS), however, this effects on FM are unclear. Aim: To evaluate the effects of a single TENS application on the autonomic cardiovascular nervous system of women with fibromyalgia. Materials and methods: Women with FM, 18 and 60 age, sedentary and no severe hemodynamic disorders received TENS at the height of star ganglion, during 30 min, frequency of 80 Hz, pulse width of 150 μs and sensorial intensity. Volunteers were evaluated by infrared thermography, active orthostatic stress test (AOST), electrocardiography, systolic, diastolic, and, mean arterial pressure (SBP, DBP and MAP). Statistical analyzes were performed in GraphPad Prism® 8.0 software, with significance for values of p ˂ 0.05 and mean ± standard error of the mean. Normality was tested using the Shapiro-wilk. The analysis followed two-way ANOVA tests, with Tukey post hoc and unpaired studant T test. A Z-score calculation was also made for the detection of outliers. Results and conclusion: There were no significant changes between the active TENS and TENS placebo, neither in relation to number of beats nor to the spectral analyzes. These findings suggest that high frequency TENS, applied in the region of the star ganglion, should not be used for modulation of sympatho-vagal activity. However, it does not offer acute adverse reactions to heart rate, ensuring its use for analgesic purposes in this population.