Anti-sépticos e Fitoterápico na cicatrização de feridas

• Ano de defesa: 2011
• Autor(a) principal: Tillmann, Mariana Teixeira
• Orientador(a): Nobre, Márcia de Oliveira
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Pelotas
• Programa de Pós-Graduação: Programa de Pós-Graduação em Veterinária
• Departamento: Veterinária
• País: BR
• Palavras-chave em Português: Qualidade cicatricial; Clorexidine 0,5%; Polivinil pirrolidona iodo 10%; Triticum
• Palavras-chave em Inglês: Healing quality; 0,5% chlorhexidine; 10% polyvinyl-pyrrolidon-iodine; Triticum
• Área do conhecimento CNPq: CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA::CLINICA E CIRURGIA ANIMAL::CLINICA VETERINARIA
• Link de acesso: https://guaiaca.ufpel.edu.br/handle/123456789/2573

The healing process comprises a dynamic cellular process that ensures the restoration tissue and the healing treatments assist in this process. The objectives of this work were evaluated the healing evolution and quality of surgical wounds treated with antiseptic and open skin wounds treated with creams containing different concentrations of Triticum vulgare. The evaluated of antiseptics was realized in dogs submitted to ovariohysterectomy and treated with 10% polyvinyl-pyrrolidon iodine (PVPI), 0,5% chlorhexidine or 0,9% physiological solution, during 10 days. The evaluated of phitotherapy was realized in rabbits being studied 135 wounds at days seven, 14 and 21 and divided in groups with ten wounds of each treatment for clinical and histopathological analysis and 15 for tensiometer analysis, the treatments were realized with aqueous extract of T. vulgare in the concentration 2mg/ml and 10mg/ml and nonionic cream, during 21 days. The surgical and open wounds were analyzed as the healing quality and climical aspect in: exudate type and quantity, epithelialization and granulation tissue formation, being that in open skin wounds was added the concentration analysis. In the open skin wounds were still realized analysis histopathological, tensile breaking strength and strength tensiometer. In the surgical wounds no observed significative difference between the treatments in clinical evaluations over the studied period. Purulent exudates occurred in all the treatments during the experimental period, although in the day 10 the wound treated with 0,9% physiological solution differed from the other treatments. (p=0,0429). The wounds treated with physiological solution allowed the stitches removal within 7 days, differed from others treatments (p=0,0357). In the evaluated of healing quality the wound treated with 0,5% chlorhexidine presented more percentage of normotrophy wounds (70%) and in to the skin anatomic limits(40%). The treatment with PVPI differed of other groups because has not wound into the skin anatomic limits (p=0,0085). In the work with open skin wounds treated with different concentration of Triticum vulgare and cream nonionic was demonstrated that the clinical analysis evolution, histopathological (phases of healing process and collagen) and tensile breaking strength have not significant difference between the groups. In the strength tensiometer analysis the treatment with Triticum vulgare 2mg/ml statistically different from the control group. (p=0,0295). In the study condition concluded that there was no difference in healing of surgical wound treated with 10% polyvinyl-pyrrolidon-iodine, 0,5% chlorhexidine or 0,9% physiological solution, although the chlorhexidine has determined highest percentage of normotrophy wound and into the normal limits. Have not difference in the healing process of open wounds treated with the two concentrations of creams containing aqueous extract of Triticum vulgare and nonionic cream, but the wound treated with cream containing aqueous extract of Triticum vulgare 2mg/ml presented better results in the strength tensiometer evaluation.