Reversão da abstinência de cafeína e performance cognitiva em mulheres consumidoras habituais de café

Detalhes bibliográficos
Ano de defesa: 2023
Autor(a) principal: Paiva, Matheus Lima de
Orientador(a): Não Informado pela instituição
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal da Paraíba
Brasil
Psicologia
Programa de Pós-Graduação em Neurociência Cognitiva e Comportamento
UFPB
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
Link de acesso: https://repositorio.ufpb.br/jspui/handle/123456789/30920
Resumo: Caffeine (1,3,7-trimethylxanthine) is a psychostimulant consumed worldwide, and its effects have been extensively investigated in various scientific fields, such as neuroscience and genetic research. This study aims to investigate the relationship between cognitive performance, withdrawal parameters, and genetic characteristics in the context of caffeine administration in regular coffee consumers. Women coffee habitual consumers (n = 30) aged between 19 and 36 participated in the study. Cognitive performance (attention and working memory) and withdrawal parameters were analyzed. According to a crossover design, all participants were subjected to both caffeine and placebo experimental groups, and the order of capsule administration was randomized for subsequent protocol effect assessment. In each experimental session, the participant arrived at the study site after 24 hours of caffeine abstinence and was assessed with the instruments before and one hour after capsule administration. The cognitive performance analysis revealed no significant differences between the caffeine and placebo sessions, although analyses according to the order of capsule administration revealed significant differences in measures of focused attention and overall attention. With the exception of two factors, all withdrawal and drowsiness parameters showed a significant decrease in the caffeine group compared to the placebo group. Regarding genetic analysis, no significant differences were observed between the genetic groups in the variation of cognitive performance after caffeine administration. On the other hand, significant differences were observed between the genetic groups for factors 4 and 5 in the caffeine administration session. From these results, it can be concluded that the influence of caffeine on cognition is less pronounced than the effects on withdrawal parameters exerted by the stimulant. Continued research into the relationship between genetic characteristics and responsiveness to caffeine beyond the study of caffeine metabolism-related genes and other factors is suggested, as well as the development of more precise theoretical models that explain how changes in caffeine metabolism can influence responsiveness to the stimulant in terms of cognitive function.