Efeitos da suplementação de Omega-3 no processo inflamatório e dano muscular induzidos por estresse físico e restrição alimentar em militares

• Ano de defesa: 2010
• Autor(a) principal: Santos., Eduardo Porto dos
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal da Paraí­ba; Brasil; Ciências da Nutrição; Programa de Pós-Graduação em Ciências da Nutrição; UFPB
• Palavras-chave em Português: Ácido Eicosapentaenóico; Ácido docosahexaenóico; Ômega-3; Proteína C reativa; Ômega-3 e exercício; Eicosapentaenoic Acid and Docosahexaenoic Acid; Omega-3 and C-reactive protein-hs; Omega-3 and exercise; CIENCIAS DA SAUDE::NUTRICAO
• Link de acesso: https://repositorio.ufpb.br/jspui/handle/tede/4309

The literature has several studies showing the anti-inflammatory and protective against cardiovascular disease, the polyunsaturated fatty acids are omega-3 intake of fatty acids has been recommended as a way to prevent heart disease and improve heart function. There are few studies involving the anti-inflammatory effect of fatty acids omega-3, with the inflammatory process triggered by physical stress of great magnitude. The effect of supplementation of polyunsaturated fatty acids (PUFA) omega-3 (n-3) in the immune response and occurrence of muscle damage in soldiers were investigated. Twenty males were divided in two groups and they received capsules contends PUFA n-3 (SUP) (n=10) or placebo (PLA) (n=10) during four weeks. in elapsing of the fourth week of supplementation, the military were submitted to a military camp with caloric ingestion and restricted rest, and elevated physical and psychological stress. The concentration of C-reactive protein (CRP-hs) was used as inflammatory marker and the occurrence of muscle damage by creatine kinase s (CK) activity. Sanguine samples were taken in four moments: 1) before supplementation; 2) before camp; 3) during camp; 4) after camp. During the three weeks of supplementation that preceded the camp s routine, was observed a significant reduction in serum CRP-hs s concentration only in group SUP. A significant increase of CK activity in the after camp, confirmed the character strenuous of this procedure. In spite of not impeding the PCR-us s increase, SUP presented a concentration of PCR-hs significantly smaller than PLA at the end of camp. These results suggest that PUFA n-3 supplementation exercises a protecting effect against the inflammatory process induced by intense physical training and alimentary restriction