Detalhes bibliográficos
| Ano de defesa: |
2021 |
| Autor(a) principal: |
Mendonça, Débora Fernanda Dutra Souto |
| Orientador(a): |
Skupien, Jovito Adiel |
| Banca de defesa: |
Correa, Marcos Britto,
Scolari, Neimar |
| Tipo de documento: |
Dissertação
|
| Tipo de acesso: |
Acesso aberto |
| Idioma: |
por |
| Instituição de defesa: |
Universidade Franciscana
|
| Programa de Pós-Graduação: |
Mestrado em Ciências da Saúde e da Vida
|
| Departamento: |
Ciências da Saúde e da Vida
|
| País: |
Brasil
|
| Palavras-chave em Português: |
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| Palavras-chave em Inglês: |
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| Área do conhecimento CNPq: |
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| Link de acesso: |
http://www.tede.universidadefranciscana.edu.br:8080/handle/UFN-BDTD/1015
|
Resumo: |
Head and neck cancer represents one of the types of neoplasms that compromise the patient's quality of life. Thus, the aim of this study was to assess the survival and the prevalence of metastases in patients diagnosed and treated with head and neck cancer and to associate with possible risk factors of patients in the Radiotherapy Sector of the Hospital Universitário de Santa Maria. Medical records of patients diagnosed with head and neck tumors, treated in the Radiotherapy sector of the Hospital Universitário de Santa Maria - HUSM during June 2013 to April 2020, were retrospectively evaluated. Three hundred and fifty-one patients were selected, where data related to the patient, the disease and the treatment were collected. Descriptive analysis was performed initially. The association among independent variables and outcomes was determined by univariate analysis, using crude odds ratios (OR). Variables with a p-value <0.20 in the univariate analysis were included in the Cox regression model by the stepwise forward method. Kaplan-Meier analysis was also used to find the sample's survival curves according to some variables. Three hundred and one medical records were included in the study, with the majority being male (84.1%) with a mean age of 63.62 years (± 2.19). Eighty-three patients died (27.6%) and 56 (18.6%) developed metastases. A significant association (p=0.046) was found between alcoholism/smoking and death. The presence of metastasis (p=0.039) and advanced cancer staging (p=0.021) also showed an association, increasing the risk of death by more than 2 times. A high prevalence of metastasis was found in the patients evaluated, which is a risk factor for death. Other variables also influenced the survival of the participating individuals. |
