USO DO CLORIDRATO DE CICLOBENZAPRINA E ACECLOFENACO NO TRATAMENTO DA DISFUNÇÃO TEMPOROMANDIBULAR: UM ENSAIO CLÍNICO RANDOMIZADO

Detalhes bibliográficos
Ano de defesa: 2023
Autor(a) principal: Rocha, Lorenzo Fogliarini da
Orientador(a): Skupien, Jovito Adiel
Banca de defesa: Blaya , Diego Segatto, Scolari , Neimar
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Franciscana
Programa de Pós-Graduação: Mestrado em Ciências da Saúde e da Vida
Departamento: Ciências da Saúde e da Vida
País: Brasil
Palavras-chave em Português:
Palavras-chave em Inglês:
Área do conhecimento CNPq:
Link de acesso: http://www.tede.universidadefranciscana.edu.br:8080/handle/UFN-BDTD/1259
Resumo: Temporomandibular dysfunction (TMD) is one of the disorders that affects the stomatognathic system of patients, directly impacting their quality of life. The aim of this clinical study was to evaluate the effectiveness of a conservative approach using a combined pharmacological therapy of muscle relaxant (cyclobenzaprine hydrochloride) and anti-inflammatory (aceclofenac) for the treatment of temporomandibular dysfunction symptoms. Parameters such as mouth opening measurement and pain pressure threshold were utilized. Thirty-five patients were evaluated, comprising 20 in the test group and 15 in the placebo group, with 25 women and 10 men (40.1 ± 11.4 years). Both groups showed improved mouth opening, decreased intensity of provoked pain, and enhanced oral health-related quality of life (p < 0.001) in the first 14 days. However, between the second and third evaluations, there was no statistically significant improvement for any of the assessed outcomes.