Pássaros domésticos no Brasil como fonte de Cryptococcus spp. : potencial risco para aquisição da criptococose

• Ano de defesa: 2020
• Autor(a) principal: Siqueira, Nathan Pereira
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Mato Grosso; Brasil; Faculdade de Medicina (FM); UFMT CUC - Cuiabá; Programa de Pós-Graduação em Ciências da Saúde
• Palavras-chave em Português: .; CNPQ::CIENCIAS DA SAUDE::MEDICINA
• Link de acesso: http://ri.ufmt.br/handle/1/4940

Cryptococcosis is an opportunistic fungal infection, caused by encapsulated yeasts belonging to the Cryptococcus neoformans and Cryptococcus gattii complex. As infections by these agents occur through inhalation of yeasts, which are usually distributed in the environment. When inhaled, these fungi reach the intimacy of the pulmonary alveoli and can generate acute infections in the pulmonary form, in addition to skin, bone infections and meningitis, that can evolve to death. The objective of this work was to isolate and characterize these agents in domestic bird excreta sold in Cuiabá, Várzea Grande e Campo Verde. 237 samples were collected from October 2018 to April 2019 and processed in the mycology/research laboratory of the Faculty of Medicine of the Federal University of Mato Grosso. Each sample was sown in ten plates containing Niger agar medium and incubated at 35oC for 72 hours. 19 of the 237 samples showed colonies suggestive of the C. neoformans/C gattii complex in addition to revealing positivity for the urease test. Using the URA5-RFLP technique, 14/19 were identified as C. neoformans (AFLP1/VNI) and 5/19 as C. deuterogattii (AFLP6/VGII). This is the first report of isolation of the agent C. deuterogattii (AFLP6/VGII) in excreta from domestic birds, reinforcing the potential risk of acquiring cryptococcosis for individuals that come into frequent contact with these animals.