Estudo Clinico e Laboratorial da Enteropatia Proliferativa Equina

Detalhes bibliográficos
Ano de defesa: 2011
Autor(a) principal: Patricia Maria Braga Baptista Soares Xavier
Orientador(a): Não Informado pela instituição
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de Minas Gerais
Brasil
VET - DEPARTAMENTO DE CLÍNICA E CIRURGIA
Programa de Pós-Graduação em Ciência Animal
UFMG
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
Link de acesso: http://hdl.handle.net/1843/42922
https://orcid.org/ 0000-0001-7376-8078
Resumo: Proliferative enteropathy (EP) is a contagious enteric disease caused by Lawsonia intracellularis. Despite having worldwide distribution in porcine, there are reports describing the presence of EP in horses in America, Europe, Australia and Japan, affecting mostly foals up to 12 months of age. There are three techniques to diagnose L. intracellularis, serology, immunochemistry of tissue samples and polymerase chain reaction (PCR). Main clinical signs described are depression, anorexia, lethargy, diarrhea, colics and occasionally death. The present study was divided into two parts, in the first part, two serology tests (immunoperoxidase monolayer assay and slide immunoperoxidase assay) were compared to determine the agreement between them. On the second part, clinical and laboratorial findings of EP affected horses were evaluated. Blood and stool samples of 315 animals of different age and gender were analysed. Whole blood count, leukocyte count, determination of protein and fibrinogen levels and creatine kinase, gama glutamyl transpeptidase, alanine aminotransferase, aspartate aminotransferase, alkalin phosphate, urea and creatinine serum levels were performed. For differencial diagnosis, eggs per gram (OPG) were realized. To confirm EP, serology through IPMA and PCR in fecal samples were performed. IPMA detected more positives than IPX. There was a fair agreement between IPMA and IPX. Twelve (3,81%) horses were positive by PCR in fecal samples, 51 (16,19%) in IPMA and two (0,63%) in both tests. Many positive horses did not have any clinical changes or laboratorial findings, showing previous contact to bacteria or presence of a subclinical disease.