Linfografia direta com corante azul patente violeta 2,5% para identificação cirúrgica dos linfonodos da cabeça, cervicais e mamários em gatos: estudo post mortem

• Ano de defesa: 2023
• Autor(a) principal: Thais Coelho Lopes
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Minas Gerais; Brasil; VET - DEPARTAMENTO DE CLÍNICA E CIRURGIA; Programa de Pós-Graduação em Ciência Animal; UFMG
• Palavras-chave em Português: Felino; Linfoma; Ciência animal
• Link de acesso: http://hdl.handle.net/1843/57202

The direct lymphography is widely used in medicine and is an important tool for identifying the sentinel lymph node in oncology. This lymph node usually corresponds to the first site of metastasis when by lymphatic dissemination. The dyes patent blue, methylene blue, and indocyanine green are the most commonly used in direct lymphography. The present study aimed at describing lymphatic drainage and identifying the sentinel lymph node in the head, neck and breast regions of cats, using the 2.5% patent blue violet dye. The application of patent blue dye was performed on cat cadavers (death within 24 hours), in predetermined regions of higher frequency of neoplasms in the feline species. After the procedure, the lymph nodes were described in terms of number, size, and macroscopic characteristics, and the specimens were histopathologically evaluated in the Pathology Laboratory of the EV-UFMG. The total number of cadavers submitted to the study was 25 cats, 12 (48%) males and 13 (52%) females. In direct lymphography of the head and neck region it was possible to identify the lymph node in 23/25 cases (92%), totaling 125 lymph nodes stained by patent blue. In the direct lymphography of the breast region, performed in 13 cats, it was possible to identify the lymph node in 12/13 cases (92.3%), totaling 32 lymph nodes stained by patent blue. Considerable anatomical variation has been observed in the number of lymph nodes present in the head and neck. One or more lymphocenters may be involved in the lymphatic drainage of a particular area. This was also observed for the breast lymph nodes, depending on where in the breast the dye was applied. Direct lymphography with patent blue dye has proven to be an efficient and fast technique for locating the lymph nodes involved in the lymphatic drainage of the head, neck, and breasts in cadavers