Avaliação da microestrutura macular, utlizando tomagrafia e coerência óptica de domínio spectral (SD-OCT) em pacientes com oclusões venosas retinianas

• Ano de defesa: 2019
• Autor(a) principal: Flavio Tepedino Aguiar Oliveira
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Minas Gerais; Brasil; Programa de Pós-Graduação em Ciências Aplicadas à Cirurgia e à Oftalmologia; UFMG
• Palavras-chave em Português: Edema macular; Oclusões venosas; Tomografia de Coerência Óptica; Edema Macular; Fator A de Crescimento do Endotélio Vascular; Injeções Intravíteas; Oclusão da Veia Retiniana; Dissertação Acadêmica
• Link de acesso: http://hdl.handle.net/1843/42111

AIMS: To compare anti-vascular endothelial growth factor (VEGF) treatment outcomes for macular edema secondary to retinal vein occlusion (RVO) based on vitreomacular adhesion (VMA). METHODS: Forty eyes of forty patients were included in this study. Best-corrected visual acuity (BCVA), central retinal thickness (CRT) and subfoveal choroidal thickness were measured in patients with retinal vein occlusion (RVO) at baseline and after 1 and 3 months of anti-VEGF treatment. Eyes were stratified by spectral-domain OCT results into two groups, VMA (+) and VMA (-). RESULTS: Twenty-four eyes were included in the VMA(-) group (60%) and sixteen eyes were included in the VMA (+) group. Both groups showed a statistically significant improvement in BCVA from baseline to month 1 and 3. When comparing the two groups, there was a more significant improvement in the VMA(+) group, whose difference was substantial at month 1. Both groups showed reduction in CRT from baseline to month 1 and 3, there was, however, no statistically important difference between the two groups. A decrease in SCT was observed in both groups from baseline to month 1 and 3, although the VMA(+) group had higher SCT at baseline. CONCLUSIONS: In this study, eyes of the VMA(+) group treated with anti-VEGF for retinal vein occlusions (RVO) had a greater improvement than eyes of the VMA(-) group, this difference was statistically significant at month 1. Both groups had a reduction in CRT and SCT, and there were no statistically significant difference between the two groups.