Qualidade de vida e saúde mental de mulheres tratadas de carcinoma invasor do colo uterino

• Ano de defesa: 2009
• Autor(a) principal: Gabriela Martins de Oliveira e Araujo Caixeta
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Minas Gerais; UFMG
• Palavras-chave em Português: Histerectomia; Qualidade de vida; Neoplasia maligna; Câncer Ginecológico; Ansiedade; Sobrevida; Carcinoma invasor do colo uterino; Radioterapia; Neoplasias; Ginecologia; Saúde mental
• Link de acesso: http://hdl.handle.net/1843/ECJS-7T5G2V

INTRODUCTION: The main objective of this study was to evaluate the quality of life and mental health of survivors of cervical neoplasm who had been treated more than two years ago with surgery radical hysterectomy (RH), non-surgical treatment chemotherapy/radiotherapy (QT/RT), or surgery and additional forms of treatment - radical hysterectomy associated with chemotherapy/radiotherapy (RH + QT/RT). It sought to compare the quality of life and mental health of female survivors of thisillness with women with no history of malignant neoplasm, and in relation to the oncological treatment provided. The secondary objective of this project was to identify variables associated with the quality of life of the women treated. METHODOLOGY: By interviewing 114 women (57 survivors and 57 control group participants), who fulfilled the criteria for inclusion and exclusion from the research, who agreed to participate and signed the Free and Informed Consent form, the research project evaluated the quality of life and mental health of the women treatedwith RH, QT/RT and RH + QT/RT, and women with no history of malignant neoplasm (the control group participants). The interview comprised of the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36), the State-Trait Anxiety Inventory (STAI), the GHQ-12 questionnaire, the Vital Events scale, and a general questionnaire to evaluate socio- demographic data. RESULTS: The age of the participants ranged from 25 to 78 years (51.1 ± 13.3). 57 women from the control group (50%) were interviewed, 11 from the RH group (9.65 %), 26 from the QT/RTgroup (22.81%) and 20 women from the RH +QT/RT (17.64%).The clinical stage of the tumour (FIGO) in the women treated was level I in 23 cases (40.36%), II in 27 (40.34%) and III in seven cases (12.30%). The four treatment groups (RH; QT/RT; RH + QT/RT; Control group) had factors in common, they had an active sexual life, were satisfied with their sexual life, could read and write, had a similar family income, were smokers or former smokers, had undergone hormonal replacement therapy, had diabetes or other illnesses, were religious, thought that their quality of life had improved over the last 10 years. Women from the QT/RT e RH + QT/RT groups had lower levels of education (84.60% and 70.00%, respectively, went to school until the fifth grade) and the average age of the groups was higher (59.2 ± 11.8 and 59.3 ± 11 respectively). Women from the QT/RT group had fewer partners (only 26%) and a higher prevalence of arterial hypertension (73.1%). Women from the RH groupshowed a greater prevalence of cardiovascular diseases (27.3%). Women from the control group presented the lowest percentage of women post menopause (24.6%). Comparison between the treatment groups and the control group showed there were no significant differences in relation to the quality of life as evaluated by the PhysicalComponent Summary (p = 0.710) and the Mental Component Summary (p = 0.581) on the SF-36 questionnaire. Among the survivors and control group participants no significant differences were found in the levels of Anxiety Trait (p = 0.910), mental health (p = 0.901) or the number of vital events experienced by the women over the last year (p = 0.079). The only difference registered between the survivors and the control group was in relation to the Anxiety State (p = 0,035*), with the average age of the control group (37.7 ± 8.9.) higher than that of the survivors. There were nosignificant differences among the 4 treatment groups (RH; QT/RT; RH +QT/RT; Control group) in terms of quality of life as evaluated by the Physical Component Summary (p = 0.078) and the Mental Component Summary (p = 0.444) on the SF-36 Questionnaire. Among the treatment groups no significant differences were registered in the levels of Anxiety Trait (p = 0.800), Anxiety State (p = 0.776), mental health (p = 0.804) or the number of vital events experienced by the women over the last year (p = 0.375). The multi-varied analysis showed a link between the followingvariables, age (OR = 1.06), arterial hypertension (OR = 3.51) and Anxiety Trait (OR = 1.11) and the physical quality of life of all the women treated for invasive carcinoma of the cervix. It also showed a link between the variables age (OR = 1.07), arterial hypertension (OR = 3.51), Anxiety Trait (OR = 1.17) and the quality of the mental health of the same women. CONCLUSION: This research project found no significant differences in relation to the general quality of life or mental health of survivors of cervical neoplasm treated more than two years ago and women with nohistory of malignant neoplasm. No differences were found in the quality of life and mental health of the women when compared to the treatment groups: surgical treatment, non-surgical treatment or surgery and an additional form of treatment.