ÍNDICE INFLAMATÓRIO DA DIETA E SUA ASSOCIAÇÃO COM SÍNDROME METABÓLICA E RESISTÊNCIA INSULÍNICA EM ADULTOS JOVENS.

• Ano de defesa: 2017
• Autor(a) principal: CARVALHO, Carolina Abreu de
• Orientador(a): SILVA, Antonio Augusto Moura da
• Banca de defesa: SILVA, Antônio Augusto Moura da , GIGANTE, Denise Petrucci , FROTA, Maria Tereza Borges Araújo , FRANÇA, Ana Karina Teixeira da Cunha , SIMÕES, Vanda Maria Ferreira
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal do Maranhão
• Programa de Pós-Graduação: PROGRAMA DE PÓS-GRADUAÇÃO EM SAÚDE COLETIVA/CCBS
• Departamento: DEPARTAMENTO DE MEDICINA I/CCBS
• País: Brasil
• Palavras-chave em Português: Índice Inflamatório da Dieta; Síndrome Metabólica; Resistência Insulínica; Adultos Jovens
• Palavras-chave em Inglês: Dietary Inflammatory Index; Metabolic Syndrome; Insulin Resistance; Young Adults
• Área do conhecimento CNPq: Saúde Publica.
• Link de acesso: https://tedebc.ufma.br/jspui/handle/tede/2025

Introduction: Several studies have documented the association between inflammation and metabolic outcomes. The Dietary Inflammatory Index (DII) is a tool to evaluate the inflammatory potential of the diet. Studies associating the DII with the metabolic syndrome or insulin resistance still controversial. Purpose: to assess the association of the DII with insulin resistance (IR) or metabolic syndrome (MS). Methods: A cross-sectional study was conducted on 2017 adults aged 23 to 25 years in Ribeirão Preto, Brazil. Food consumption was assessed using a validated Food Frequency Questionnaire. The DII was calculated from 35 available food parameters. IR was determined from the classification of HOMA-IR values (≥2.7uU mL-1). MS was diagnosed based on the Joint Interim Statement (JIS) criterion. The association of DII score with IR or MS was determined by Poisson regression analysis with robust estimation of variance. The variables included in the multivariable model were selected from Directed Acyclic Graphs (DAG). Results: The diet of the young adults studied showed a high inflammatory potential, with a mean DII of 1.10 (range: -4.69 to +5.28). The prevalence of MS was 12.2% and of IR was 12.3%, both greater in males. In adjusted analysis, the DII was not associated with IR or MS in either sex. Conclusions: Although this association was not detected in this sample of young adults, the study demonstrated that their diet had a high inflammatory potential, a fact that may increase the risk for the development of non-communicable diseases in the future.