DETECÇÃO DE DNA-HPV NA MUCOSA ORAL E SUA ASSOCIAÇÃO COM DNA-HPV GENITAL

• Ano de defesa: 2012
• Autor(a) principal: Vidotti, Lisandra Rocha
• Orientador(a): LOPES, Fernanda Ferreira
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal do Maranhão
• Programa de Pós-Graduação: PROGRAMA DE PÓS-GRADUAÇÃO EM SAÚDE MATERNO-INFANTIL
• Departamento: saúde da mulher e saúde materno-infantil
• País: BR
• Palavras-chave em Português: HPV; Cavidade oral; Genital; PCR-nested
• Palavras-chave em Inglês: HPV; Oral cavity; Genital; Nested PCR
• Área do conhecimento CNPq: CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA
• Link de acesso: http://tedebc.ufma.br:8080/jspui/handle/tede/1166

Background: Human Pappilomavirus infection is one of the most common sexually transmitted disease, and can be found at various anatomical sites, such as the anogenital tract, skin, larynx, conjunctiva, tracheobronchial mucosa, esophagus and oral cavity. The path of HPV transmission to the oral cavity is not completely understood, and so many studies are being undertaken aiming to clarify if the genital infection by the virus may be a predisposing factor. Methodology: This is a cross-sectional cohort study. The sample consisted of women attending in ambulatory of the Centro de Pesquisas Clínicas-CEPEC / HUUFMA. After signing the TCLE, all patients answered a questionnaire about social information, medical history, smoking habits, alcohol consumption and sexual behavior and were also subjected to collection of cellular material from the oral cavity and genital area for research of Desoxirribonucleic Acid by polymerase chain reaction technique (PCR). Results And Conclusions: The prevalence of human papillomavirus in the oral cavity was higher in women with genital HPV. With a significant association between the presence of oral HPV DNA and genital HPV DNA: The practice of oral sex, smoking and drinking were not related to the presence of HPV DNA in the oral cavity.