Estudo da composição corporal, parâmetros bioquímicos, imunológicos e qualidade de vida em mulheres climatéricas em um município no nordeste do Brasil

• Ano de defesa: 2016
• Autor(a) principal: Maniçoba, Anna Cyntia Brandão Nascimento
• Orientador(a): BRITO, Luciane Maria Oliveira
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal do Maranhão
• Programa de Pós-Graduação: PROGRAMA DE PÓS-GRADUAÇÃO EM SAÚDE DO ADULTO E DA CRIANÇA/CCBS
• Departamento: DEPARTAMENTO DE MEDICINA I/CCBS
• País: Brasil
• Palavras-chave em Português: Composição corporal; Parâmetros bioquímicos, imunológicos; Qualidade de vida; Mulheres climatéricas
• Palavras-chave em Inglês: Body composition; Biochemical, immunological parameters; Quality of life; Climacteric women
• Área do conhecimento CNPq: Ginecologia e Obstetrícia; Endrocrinologia
• Link de acesso: http://tedebc.ufma.br:8080/jspui/handle/tede/1421

The climacteric is the organic phase comprising the transition from the reproductive period and not reproductive, may start at age 35 and extend to 65, studying with hormonal changes that impact on different organ systems and quality of life. This study aimed to assess the body composition (anthropometry and bioimpedance), biochemical profile (fasting glucose, total cholesterol, LDL, HDL, VLDL, triglycerides, PCR) hormonal profile (FSH, LH, estradiol and progesterone), immunological profile (leptin IL-2, IL-4, IL-6, IL-10, TNF, IFN-, IL-17), and quality of life in climacteric women. We conducted a case-control study with postmenopausal women in the case group and the control group who had not yet entered menopause. 136 women were included, 52 (38.2%) in the group of menopausal and 84 patients (61.8%) in patients not menopausal Statistical analysis was performed with the following tests: Chisquare, Mann-Whitney and t Student. No significant differences were found in relation to quality of life, hypertension, assessment of body composition (bioimpedance, anthropometric parameters BMI), CRP levels, triglycerides, HDL and VLDL. We found significant differences in leptin levels with significantly higher values in the group of postmenopausal women compared to women not menopausal., Indicating that leptin is important immune parameter in the evaluation of climacteric women by regulating the homeostasis of the organism.