Pré-hipertensão e vitamina D

Detalhes bibliográficos
Ano de defesa: 2017
Autor(a) principal: CANTANHÊDE, Jacqueline Martins lattes
Orientador(a): FIGUEIREDO NETO, José Albuquerque de lattes
Banca de defesa: CABRAL, Nayra Anielly Lima lattes, MONTEIRO, Sally Cristina Moutinho lattes, VIDAL, Flávia Castello Branco lattes
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal do Maranhão
Programa de Pós-Graduação: PROGRAMA DE PÓS-GRADUAÇÃO EM SAÚDE DO ADULTO E DA CRIANÇA/CCBS
Departamento: DEPARTAMENTO DE MEDICINA II/CCBS
País: Brasil
Palavras-chave em Português:
Palavras-chave em Inglês:
Área do conhecimento CNPq:
Link de acesso: https://tedebc.ufma.br/jspui/handle/tede/2040
Resumo: The Prehypertension is characterized with systolic blood pressure levels between 120 - 139 mmHg and diastolic blood pressure 80-89mmHg, considered an intermediate state for the development of arterial hypertension. Detecting risk factors for prehypertension becomes important to prevent thousands of premature deaths. Vitamin D deficiency has been linked to high blood pressure and consequently to cardiovascular diseases that are responsible for high global morbidity and mortality. Thus, the analysis of the relationship between prehypertension and vitamin D is fundamental because it allows preventive intervention and avoids the progression to hypertension, thus reducing morbidity and mortality due to cardiovascular diseases. The present study aims to evaluate the association between serum 25 (OH) D levels and prehypertension. This is a cross-sectional study with a quantitative approach carried out at the Hospital Universitário da Universidade Federal do Maranhão in São Luís, Maranhão, Brazil. The 161 adults with prehypertensive and normotensive conditions participated in this study. Socio-demographic, anthropometric, behavioral and clinical data of the participants of both genders between 30 and 50 years old were used. Statistical analysis was performed using SPSS® software version 23. Data were treated using descriptive procedures. The Kolmogorov-Smirnov test was used to verify the normality of the variables. The results were considered statistically significant if p <0.05. In relation to the cardiometabolic risk factors, there was a statistically significant difference (p <0.05) between the control group and the study in the parameters evaluated (BMI, WC and WHtR). The prehypertensive group had a higher mean. Participants with excess weight have statistically higher odds of presenting prehypertension (OR = 3.62, 95% CI = 1.79-7.31 p <0.001). Regarding the Cardiometabolic Risk Factors stratified by gender, a statistically higher percentile was observed in females. Regarding systolic and diastolic blood pressure and vitamin D, there was a statistically significant difference (p <0.05) in all variables analyzed. For males, there was no statistically significant difference in the vitamin D variable. Mean SBP and DBP, and vitamin D (36.15 ± 12.31), were higher in the study group. Especially women (33.65 ± 10.41). In this study, the association of vitamin D and the presence of prehypertension was not observed. The serum vitamin D level of most participants was considered adequate. The female population had a higher prevalence of increased cardiometabolic levels and a higher prevalence of inadequate levels of vitamin D. There was no correlation between serum vitamin D levels with anthropometric data and blood pressure levels.