Detalhes bibliográficos
| Ano de defesa: |
2012 |
| Autor(a) principal: |
PACHECO, Jairo Sousa
 |
| Orientador(a): |
TORRES, Orlando Jorge Martins
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| Banca de defesa: |
Não Informado pela instituição |
| Tipo de documento: |
Dissertação
|
| Tipo de acesso: |
Acesso aberto |
| Idioma: |
por |
| Instituição de defesa: |
Universidade Federal do Maranhão
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| Programa de Pós-Graduação: |
PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS DA SAÚDE/CCBS
|
| Departamento: |
DEPARTAMENTO DE MEDICINA I/CCBS
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| País: |
Brasil
|
| Palavras-chave em Português: |
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| Palavras-chave em Inglês: |
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| Área do conhecimento CNPq: |
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| Link de acesso: |
https://tedebc.ufma.br/jspui/handle/tede/1997
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Resumo: |
Objective: To determine the major complications in patients undergoing gastroduodenopancreatectomy for pancreatic cancer and periampullary region, possible determinant factors and associated mortality. Methods: Retrospective study including patients diagnosed with pancreatic cancer and periampullary region undergone GDP from January 1987 to December 2007. Epidemiological and clinical data, laboratory and disease-related data and the procedure were reviewed. Results: 105 patients were included. Males represented 52%. Signs and/or symptoms more frequent were pain and jaundice. Jaundice was observed in 78.89%. Most didn´t have diabetes, and the use of alcohol and smoke was less frequent. Most were submitted to classical resection with median operative time of 440 minutes. Duct-to-mucosa pancreatic reconstruction was carried out in 69 patients. Complications were observed in 54 patients (51.4%). The mortality rate was 7.6% (eight patients). Pancreatic fistula was observed in 21 cases (20%), with 9 cases (8.5%) grade A, 2 (1.9%) grade B, and 10 (9.5%) grade C. Other complications observed were biliary fistula (5.7%), operative wound infection (5.7%), intraabdominal abscess/collection (5.7%) and hemoperitoneum (2.8%). Clinical complications observed were pneumonia (3.8%) and urinary tract infection (1.9%). High CA 19-9 tumor marker and duct-to-mucosa pancreatic enteric reconstruction technique presented a statistically significant result. Conclusion: Pancreatic fistula remains the most important complication associated with higher mortality. The surgical technique used and CA 19-9 were prognostic factors. In this study, the pancreatic reconstruction technique using ductto-mucosa anastomosis type presented less failure. |
