Avaliação cardíaca morfofuncional na doença renal crônica estágios 3 e 4

• Ano de defesa: 2014
• Autor(a) principal: Bernardes, Waleska Alves de Oliveira de Queiroz
• Orientador(a): Rassi, Salvador
• Banca de defesa: Rassi, Salvador, Jardim, Paulo Cesar Brandão da Veiga, Sousa, Mauri Félix de
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Goiás
• Programa de Pós-Graduação: Programa de Pós-graduação em Ciências da Saúde (FM)
• Departamento: Faculdade de Medicina - FM (RG)
• País: Brasil
• Palavras-chave em Português: Doença renal crônica; Risco cardiovascular; Alterações cardíacas morfo-funcionais
• Palavras-chave em Inglês: Chronic kidney disease; Cardiovascular risk; Cardiac morphofunctional alterations
• Área do conhecimento CNPq: CLINICA MEDICA::NEFROLOGIA
• Link de acesso: http://repositorio.bc.ufg.br/tede/handle/tede/6795

CKD is a public health issue, with an estimated prevalence of 10% worldwide. Recently, the CKD was founded like an important cause of premature mortality, especially that caused by cardiovascular disease. This study intent was to identify and quantify cardiac morphofunctional alterations, and to verify the association between echocardiographic parameters and clinical variables, in a population with CKD stages G3A, G3B and G4, at conservative treatment. It is a cross-sectional study, including 55 patients with CKD stable disease for at least 1 year. We evaluated anthropometric measures, blood pressure values, creatinine, glomerular filtration rate, CKD stage, urine albumin-to-creatinine ratio, serum albumin, lipid profile, serum phosphorus, serum calcium, PTH levels, hemoglobin levels, Creactive protein levels, smoking, hypertension, diabetes and established cardiovascular disease. We observed high frequency of diastolic dysfunction (80%) and left ventricular hypertrophy (52,7%). The frequency of systolic dysfunction was 9,1% and valve cardiac calcification was 41,8%. Only one echocardiographic measure – the velocity of Sm wave – presented association with CKD stage. This measure is a marker of early systolic dysfunction. Neither the other echocardiographic parameters nor the presence of cardiac morphofunctional alterations presented association with CKD-related risk factors, only with traditional cardiovascular risk factors.