Associações binárias de timol, carvacrol e eugenol para o controle de fases imaturas de vida livre de Amblyomma sculptum

Detalhes bibliográficos
Ano de defesa: 2020
Autor(a) principal: Silva, Francisca Letícia Vale da lattes
Orientador(a): Monteiro, Caio Márcio de Oliveira lattes
Banca de defesa: Monteiro, Caio Márcio de Oliveira, Lopes, Welber Daniel Zanetti, Ferreira, Lorena Lopes
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de Goiás
Programa de Pós-Graduação: Programa de Pós-graduação em Ciência Animal (EVZ)
Departamento: Escola de Veterinária e Zootecnia - EVZ (RG)
País: Brasil
Palavras-chave em Português:
Palavras-chave em Inglês:
Área do conhecimento CNPq:
Link de acesso: http://repositorio.bc.ufg.br/tede/handle/tede/10935
Resumo: His study aimed to evaluate whether the associations between thymol, carvacrol and eugenol on the immature life stages of Amblyomma sculptum have a synergistic effect, by means of in vitro test and under semi field conditions, as well as to evaluate the cost-benefit ratio of formulations. To assess the synergism, the substances were tested in vitro in isolation and associated at concentrations of 0.3125; 0.625; 1.25; 2.5; 5.0 and 10.0 mg/mL on non-fed larvae; and 2.5; 3.75; 5.0; 7.5; 10.0; 15.0 and 20 mg/mL on non-fed nymphs. For the test in semi field conditions, the two associations that obtained the best efficacy in in vitro tests were selected for application on plots of Panicum maximum artificially infested with A. sculptum larvae. In in vitro tests with larvae, the association between thymol and eugenol demonstrated synergistic effect at all tested concentrations; treatments associating thymol + carvacrol and eugenol + carvacrol demonstrated synergistic effect at a concentration of 5.0 mg/mL. In in vitro tests with nymphs, the association between thymol + eugenol showed synergistic effect at a concentration of 5.0 mg/mL; the association between thymol + carvacrol resulted in a synergistic effect at a concentration of 10.0 mg/mL while treatments with the association of carvacrol + eugenol showed moderate synergism at concentrations of 5.0; 7.5 and 10.0 mg/mL. The association of the substances allowed lower use to achieve mortality rates higher than 95% in in vitro tests, resulting in cost reduction. In semi field conditions the efficacy of the associations was 63.2% for thymol + eugenol association and 42.6% for carvacrol + eugenol association. Thus, depending on concentration, synergistic effects of binary associations between thymol, carvacrol and eugenol were observed for immature stages of A. sculptum, in addition to allowing cost reduction with the active principle for formulation development.