Atividade antimicrobiana e produção de enzimas de interesse biotecnológico de bactérias isoladas de diferentes habitats.

Detalhes bibliográficos
Ano de defesa: 2009
Autor(a) principal: RODRIGUES, Ariana Alves lattes
Orientador(a): VIEIRA, José Daniel Gonçalves lattes
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de Goiás
Programa de Pós-Graduação: Mestrado em Ciências da Saúde
Departamento: Ciências da Saúde - Medicina
País: BR
Palavras-chave em Português:
Palavras-chave em Inglês:
Área do conhecimento CNPq:
Link de acesso: http://repositorio.bc.ufg.br/tede/handle/tde/1719
Resumo: The microorganisms are essential for the environment and contribute to stabilize the environments, playing a hole in the basic ecologic process such as biogeochemistry cycles and food chains, and sometimes responsible for the maintenance of the ecologic relationship between the organisms. So we have a diversity of microorganism and in consequence bioactive molecules that they produce as a result of primary and secondary metabolism, and are used by humans in many important social-economic activities, which includes the search for new medicines and new enzymes with biotechnology interest. This study analyzed different microorganisms isolated from different habitats, and the objective was select microorganisms with the capacity of inhibit the growing of pathogenic microorganisms and that produces enzymes with biotechnological applications. The isolates antimicrobial and enzymatic activities were evaluated, bioactive substances extracted and the cytotoxic activity with Artemia salina determined. The biggest part of the isolates produces substances with antimicrobial activity for the evaluated gram-positives, and none are toxic in low levels. The isolates are great producers of esterases and β-glucosidades. The isolates described in this study are from four different environments: Cerrado soil, Mata Atlântica, Azadirachta indica A. JUSS (Nim) e cave environment and are related to unique environmental conditions, the majority part of the isolates are able to produce molecules with biotechnology activity, this suggests a great microbial potential for the production of bioactive molecules that can be used in industries and medicine. Key Words: Antimicrobial activity, microorganisms, enzymes, bioactive.