Efeito de um extrato aquoso de folhas e talos de beterraba (beta vulgaris) orgânicos sobre a lipemia pós-prandial e marcadores de distúrbios pressóricos em indivíduos com dislipidemia

• Ano de defesa: 2016
• Autor(a) principal: Gomes, Anna Paula Oliveira
• Orientador(a): Botelho, Patrícia Borges
• Banca de defesa: Faria, Eliana Cotta de, Cominetti, Cristiane, Botelho, Patrícia Borges
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Goiás
• Programa de Pós-Graduação: Programa de Pós-graduação em Nutrição e Saúde (FANUT)
• Departamento: Faculdade de Nutrição - FANUT (RG)
• País: Brasil
• Palavras-chave em Português: Dislipidemias; Doenças cardiovasculares; Polifenóis; Beta vulgaris
• Palavras-chave em Inglês: Dyslipidemia; Ardiovascular disease; Polyphenols; Beta vulgaris
• Área do conhecimento CNPq: CIENCIAS DA SAUDE::NUTRICAO
• Link de acesso: http://repositorio.bc.ufg.br/tede/handle/tede/9789

Aim: To analyze whether the acute effect of an aqueous extract of beet leaves and stalks containing different concentrations of polyphenols on lipemia and markers of blood pressure disorders in dyslipidemic subjects after a high-fat meal. Methods: In a randomized, double-blind, placebo-controlled crossover design, 13 dyslipidemic subjects were fed a single high-fat meal and supplemented with placebo or aqueous extract of organic beet leaves and stalks (31.96 mg or 77.53 mg of polyphenols) with 1-week wash-out period. Blood samples were obtained at fasting and 30, 60, 120 and 180 min after intervention. Total cholesterol, HDL, triglycerides, glucose, insulin, nitric oxide and blood pressure were assessed. Results: High fat meal increased triglycerides after 120 (P < 0.001) and 180 minutes (P < 0.001) and reduced HDL after 30 minutes. This reduction was attenuated in both groups that received aqueous extract of beet leaves and stalks after 120 minutes (P = 0.005). There were no treatment differences in triglycerides, glucose, insulin and nitric oxide levels in all times. In contrast, it was observed a reduction in diastolic blood pressure from baseline (T0) in both groups that received aqueous extract of beet leaves and stalks. Conclusion: The aqueous extract of beet leaves and stalks containing only 31.96 mg of polyphenols was able to attenuate the reduction of HDL induced by a high fat meal similarly to extract containing a higher polyphenols concentration.