Detalhes bibliográficos
| Ano de defesa: |
2009 |
| Autor(a) principal: |
OLIVEIRA, Pollyanna Laurindo de
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| Orientador(a): |
OLIVEIRA, Cecilia Maria Alves de
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| Banca de defesa: |
Não Informado pela instituição |
| Tipo de documento: |
Dissertação
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| Tipo de acesso: |
Acesso aberto |
| Idioma: |
por |
| Instituição de defesa: |
Universidade Federal de Goiás
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| Programa de Pós-Graduação: |
Mestrado em Química
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| Departamento: |
Educação em Química
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| País: |
BR
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| Palavras-chave em Português: |
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| Palavras-chave em Inglês: |
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| Área do conhecimento CNPq: |
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| Link de acesso: |
http://repositorio.bc.ufg.br/tede/handle/tde/1062
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Resumo: |
Amaioua guianensis Aulb is a shurb best known as marmelada-brava or marmelinho-vermelho belonging to Rubiaceae family. Amaioua genus comprise 10 species which are distributed through Floresta Amazônica, Cerrado, Pantanal and Mata Atlântica. No phytochemical work has been reported on the leaves and bark of A. guianensis. As part of our ongoing search for new compounds from higher plants we undertaken and investigation of the ethanolic extract of A. guianensis as well as their antioxidant na molluscicidal activity. In this study we describe the isolation and structural elucidacion of a new conpound, a cyclopeptide (2), and twelve known compounds: a coumarin (1), two pentacyclic triterpene (3 and 4), mannitol (5), ethylglucose (6), three chorogenic acids (7, 8 and 9), two proanthocyanidins (10 and 11) and two steroids (12 and 13). The crude ethanolic extract, its purified fractions soluble in n-hexane, ethylacetate and methanolic, besides compounds 10 and 11 promptly reacted with DPPH leading to a loss of 50% in the absorbance activity in the concentrations of 78, 25, 246 and 4 μg/mL, respectively. The results of the molluscicidal assays with the crude ethanolic extract and its fractions indicated that ethylacetate fractions is the most active fraction with LC100 100 ppm and LC50 42,5 ppm |
