Persistência de anticorpos protetores após sete anos de imunização contra hepatite b em lactentes em Goiânia – GO

Detalhes bibliográficos
Ano de defesa: 2015
Autor(a) principal: Oliveira, Laura Ferreira lattes
Orientador(a): Junqueira, Ana Luiza Neto lattes
Banca de defesa: Junqueira, Ana Luiza Neto, Vieira, Maria Aparecida da Silva, Minamisava, Ruth, Matos, Marcia Alves Dias de, Souza, Marcia Maria de
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de Goiás
Programa de Pós-Graduação: Programa de Pós-graduação em Enfermagem (FEN)
Departamento: Faculdade de Enfermagem - FEN (RG)
País: Brasil
Palavras-chave em Português:
Área do conhecimento CNPq:
Link de acesso: http://repositorio.bc.ufg.br/tede/handle/tede/5433
Resumo: To assess the persistence of anti-HBs protective titers after seven years of primary immunization in children who received the first dose of the Brazilian vaccine against Hepatitis B within the first 12 hours of life and who achieved protective titers after 30-45 days of vaccination (GMT = 491.78 mIU / mL), blood samples were collected between 2014 and 2015 in 147 children. Concurrently held evaluating the persistence of protective titers correlate the application site of VLC vaccine (vastu lateral thigh) or VG (ventrogluteal). Was found that 66,2% of these had no protective titers of anti-HBs, presenting GMT = 6.75 mIU / mL. A positive correlation was found between high levels of anti-HBs after primary vaccination and after seven years (rho Spearman = 0.446, p = <0.0001). None of the participants was positive for anti-HBc marker. When compared to the presence of protective titers between the two vaccine sites of application, there wasn't difference between the two groups (p = 0.756). Keywords: hepatitis B; Anti-hepatitis B antibodies; Immunization; Intramuscular injections.