Função e integridade renal de cães com diabetes mellitus

• Ano de defesa: 2012
• Autor(a) principal: Silva, Andréa Cruvinel Rocha
• Orientador(a): Fioravanti, Maria Clorinda Soares
• Banca de defesa: Fioravanti, Maria Clorinda Soares, Kogika, Márcia Mery, Duque, Celina Tie Nishimori
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Goiás
• Programa de Pós-Graduação: Programa de Pós-graduação em Ciência Animal (EVZ)
• Departamento: Escola de Veterinária e Zootecnia - EVZ (RG)
• País: Brasil
• Palavras-chave em Português: Caninos; Diagnóstico precoce; Doença renal crônica; Nefropatia diabética; Canine; Chronic kidney disease; Diabetic nephropathy; Early diagnosis
• Área do conhecimento CNPq: PATOLOGIA ANIMAL::PATOLOGIA CLINICA ANIMAL
• Link de acesso: http://repositorio.bc.ufg.br/tede/handle/tede/3145

Early diagnosis of diabetes mellitus (DM) in dogs or recognition of complications helps to increase the survival rate of animals. In human kidney complications caused by diabetes are well established, unlike canines. This study aimed to determine whether dogs with DM develop changes that lead to renal disease. We studied 31 diabetic dogs, which were divided into three groups, G1 realized that dogs without DR, G2, with urinary tract infection (UTI) and G3, with DR in stage 1. The evaluation consisted of history of animals, clinical examination, measurement of systolic arterial pressure (SAP) and laboratory tests: blood count, urinalysis, blood biochemistry (fibrinogen, glucose, urea, creatinine, total protein, albumin, globulin, phosphorus, calcium, sodium, potassium, fructosamine and cholesterol) and urine biochemistry (protein, creatinine, sodium, potassium and determined the activity of gama glutamiltransferase - GGT). Established the UPC and fractional excretion (EF) of sodium and potassium. The results show relation between DM and DR and the most relevant were found ITU and increase in the UPC, serum phosphorus, urinary GGT, cholesterol, fibrinogen and EF sodium and potassium. About the clinical signs observed polyuria, polydipsia, cataracts, polyphagia, weight loss, dehydration, and neoplasms. Dogs with a mean age of nine years, females, and the Poodle are more predisposed to diabetes. Dogs that have received specific diets, as well as laboratory monitoring, managed glycemic control and improved quality of life.