Critérios para classificação e análise clínico- patológica comparativa entre líquen plano oral, lesões de aspecto liquenoide e leucoplasia verrucosa proliferativa em cavidade oral

• Ano de defesa: 2019
• Autor(a) principal: Miguel, Fernanda Cardoso Doyle Maia
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal do Espírito Santo; BR; Mestrado Profissional em Clínica Odontológica; Centro de Ciências da Saúde; UFES; Programa de Pós-Graduação em Clínica Odontológica
• Palavras-chave em Português: Liquen plano bucal; Leucoplasia oral; Neoplasias bucais; Lichen planus; Oral; Leukoplakia oral; Mouth neoplasms; subject.br-rjbn; Odontologia
• Link de acesso: http://repositorio.ufes.br/handle/10/13508

Lichen planus is a mucocutaneos disease of unknow etiology and when it is in the oral cavity, it is named oral lichen planus (OLP). Early diagnosis and follow-up are necessary due to the potential for malignant transformation of these lesions and differential diagnosis with other lesions, such as leukoplakia and proliferative verrucous leukoplakia (PVL). Objective: To survey and review cases of OLP and leukoplakia, as well as to compare sociodemographic and clinicopathologic features among OLP, oral lichenoid lesion (OLL) and PVL. Method: A longitudinal and observational study was perfomed in which oral leukoplakia and OLP obtained from the UFES Oral Pathology database from 2009 to 2016 were reclassified into OLP, OLL, lichenoids reactions (LR) and PVL. Sociodemographic and clinicopathologic data were collected, and lesions compared using the chi-square or Fisher’s exact test. For data analysis, P values0,05 were considered significant. Results: The population consisted of 223 cases, among which 74 were OLP cases and 151 leukoplakia cases. After classification, according to criteria proposed in the study, 15 cases of OLP, 15 OLL, 2 LR and 11 PVL were evaluated. Maximum follow-up period was 102 months. OLP and LVP ocurred significantly more in women than OLL. Wickham striae (p