Biossíntese otimizada de nanopartículas de ouro com extrato de Virola oleifera

• Ano de defesa: 2016
• Autor(a) principal: Ferreira, Débora Machado
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal do Espírito Santo; BR; Mestrado em Biotecnologia; Centro de Ciências da Saúde; UFES; Programa de Pós-Graduação em Biotecnologia
• Palavras-chave em Português: Green synthesis; Nanotechnology; Gold nanoparticles; Factorial design; Síntese verde; Nanotecnologia; Nanopartículas de ouro; Planejamento fatorial; Virola oleifera; Biotecnologia; 61
• Link de acesso: http://repositorio.ufes.br/handle/10/7087

Nanotechnology has received very attention in recent decades due to their promising applications. The nanoparticles have applications in several areas, such as in the pharmaceutical field (delivery systems for pharmaceuticals, cosmetics); textile industry (clothing with antimicrobial properties); dignostic medicine (image, high efficiency biosensors); energy (solar panels); bioremediation, among others. Conventional synthesis of nanoparticles may involve chemical and physical expensive that often use toxic materials with potential risks such as environmental toxicity, cytotoxicity, and carcinogenicity. The toxicity problems arise from substances such as organic solvents, reducing agents and stabilizers that are used to prevent agglomeration of the colloids. As a result, these agents toxicity of the synthesized nanoparticles can prevent its biomedical application. However, all these factors can be controlled by biologically mediated production. Therefore synthesis of nanomaterials using plant extracts is shown a quick and non-toxic method for producing metal nanoparticles. This method, also called Green synthesis search the use of natural compounds as reducing agents, providing a sustainable alternative to toxic products. Here we propose a green synthetic route for the preparation of gold nanoparticles in the presence of a resin Virola oleifera based on factorial design with as variable concentration of extract and pH. Characterized using UV-vis spectroscopy, Raman spectroscopy, FT-IR, TEM, DLS and zeta potential. In this case, the plant extract used was capable of reducing the metal salt, the absorption spectrum observed in the UV-vis region and provide stability. Nanoparticles were functionalized with the plant extract was used as seen in profile analysis showing bands of chemical bonds which occur in hybrid systems AuNPs. Also they showed good dispersivity and homogeneous size. We hope this study will contribute as an alternative to traditional routes and has a promising biological application.