Efeito da terapia a laser de baixa potência no reparo de defeitos ósseos preenchidos com osso bovino inorgânico: estudo em calvária de ratos

• Ano de defesa: 2019
• Autor(a) principal: Santos, Matheus Ambrosio Freitas Martins dos
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal do Espírito Santo; BR; Mestrado Profissional em Clínica Odontológica; Centro de Ciências da Saúde; UFES; Programa de Pós-Graduação em Clínica Odontológica
• Palavras-chave em Português: Regeneração óssea; Terapia a laser de baixa potência; Defeitos ósseos críticos; Enxerto ósseo; Biomateriais; Bone regeneration; Low-level laser therapy; Critical bone defects; Bone grafting; Biomaterials; subject.br-rjbn; Odontologia
• Link de acesso: http://repositorio.ufes.br/handle/10/13587

Objective: To evaluate the effect of the number of sessions of Low Level Laser Therapy (LLLT) in the amount of formed bone in critical size defects (CSD) filled with inorganic bovine bone (IBB) or blood clot. Methodology: Forty two male rats were divided into four groups according to the number of sessions: control (no irradiated), L4 (four sessions), L7 (seven sessions), L11 (eleven sessions). Two CSD defects were produced in each calvaria and filled with blood clot or IBB. The two cavities were irradiated with the same dosimetric parameters. The sessions started immediately after surgery and were maintained at 48 h intervals. The animals were euthanized 15 to 30 days after surgery. Data were analyzed by the one-way ANOVA with post hoc Tukey test. Results: After 15 days in the defects with blood clot, only the L7 group showed significantly higher bone formation (49.74%) compared to the control group (26.96%), (P 0.05). In the cavities filled with IBB, after 15 days there was significantly higher bone formation in L4 (30.55%) and L7 (35.12%) compared to the control group (22.3%) (P 0.05). After 30 days the percentage of neoformed bone was statistically higher only in the L7 (51.94%) and L11 (52.19%) groups, compared to the control group (37.38%), (P