Colonização em gestantes e infecção neonatal por Streptococcus do grupo B

• Ano de defesa: 2009
• Autor(a) principal: Ventura, Maria Sidneuma Melo
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Palavras-chave em Português: Streptococcus agalactiae; Ruptura Prematura de Membranas Fetais; Trabalho de parto prematuro
• Link de acesso: http://www.repositorio.ufc.br/handle/riufc/1322

The objectives of this study: to identify the prevalence and the risk factors from maternal colonization and neonatal infection from group B Streptococcus in women with preterm labor and/or premature rupture membranes. It measures and compare vaginal and anorectal colonization rates. It compare detection rates with selective and non-selective culture media and it compare detection rates with blood ágar and CPS ágar. A transversal study of 112 women and 220 newborns was performed at Maternidade Escola Assis Chateaubriand from Universidade Federal do Ceará (MEAC-UFC) from may /2008 to july/2009. Vaginal and anorectal samples from each woman were collected using sterile swabs. In 71 women two swabs (vaginal and anorectal) were placed separately in Stuart transport medium and two swabs (vaginal and anorectal) were inoculated separately in Todd-Hewitt selective medium. All subcultered in blood agar plates. The other pregnancies 41 women were investigated only in selective medium and subcultered in a CPS agar plates. A blood culture was collected from each preterm newborn that with any sign of infection. The maternal colonization rate from 71 women was of 4,2% and from the 41 women group was of 17%. Todd-Hewitt selective medium detected 4,4% and non-selective medium 7,2% GBS positive culture (not statistical relevant –NSR). Vaginal samples had a detection rate of 10,7% and anorectal samples had detection rate of 7,1% ( NSR). Urinary infection and be a housewife showed to be meaningful risk factors (p < 0,05). From the newborns studied none of them had GBS positive blood culture due to the sign of infection and altered hemogram. It,s possible that the result had occurred for the fact that the mothers had taken antibiotic before or during the labor. The GBS women colonization in our environment is similar to the other regions of Brazil. The GBS could be to here an important agent for neonatal infection disease and its necessary to take serious prevent measures.