Análise da saúde oral, perfil clínico, bioquímico e fatores sociodemográficos entre indivíduos com Hiperparatireoidismo Primário Esporádico ou associado à Neoplasia Endócrina Múltipla Tipo 1

• Ano de defesa: 2018
• Autor(a) principal: Cardoso, Fabiana Brandão Paim
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Palavras-chave em Português: Saúde Bucal; Hiperparatireoidismo Primário; Perfil de Saúde; Bioquímica
• Link de acesso: http://www.repositorio.ufc.br/handle/riufc/33149

Introduction: Primary hyperparathyroidism (HPTP) is considered the third most common endocrinopathy, affects 1-3% of postmenopausal women and has a total incidence in the adult population of 21.6 cases per 100,000 people. HPTP can affect the skeleton and cause maxillomandibular bone changes, dental and periodontal structure. Objective: To analyze oral health, biochemical profile and sociodemographic factors among individuals with PHPT. Patients and methods: An observational and cross-sectional study was performed with 49 patients diagnosed with PPH associated with multiple endocrine neoplasia type 1 (group 1; G1) or sporadic HPTP (group 2; G2) from the Outpatient Clinic of Endocrinology and Diabetology, University Hospital Walter Cantídio-UFC. The inclusion and exclusion criteria were obeyed. The oral aspects investigated were: periodontal parameters, salivary flow, presence of decayed, missing and filled teeth, as well as the presence of torus. In addition, the following biochemical parameters: calcium ion (Cai ++), total calcium (Ca ++), phosphorus (P), parathormone (PTH), alkaline phosphatase (FA), magnesium (Mg) and calciuria were collected in a period close to dental evolution. Socio-demographic data such as age, marital status, naturalness, profession, schooling, family income, socioeconomic class were also collected. Data were expressed as mean, standard deviation, absolute and percent frequency, and Student's t test, Fisher's exact and Pearson's X2, and were analyzed using the software program SPSS ® 20.0, adopted p <0.05. Results: In the G1 group, 30 individuals with an age of 40 ± 13.7 years (range 17-76 years) were interviewed. Twenty women were evaluated in G2, 19 of which were women, with a mean age of 63.8 ± 15.5 years (range 19-86 years). The degree of mobility (p = 0.003), grade 2 bleeding index (p = 0.001), grade 2 plaque index (p <0.001), depth of probing (p <0.001), level of insertion loss (p <0.001), presence of palatine torus (p = 0.016) and gingival margin (p = 0.001) were higher in G1. G1 presented higher frequency of lost tooth loss (> 20 missing teeth), teeth with active and / or inactive caries (p = 0.001) and enamel rupture (p = 0.024). There were no differences in the means of PTH, Cai ++ and Ca ++. The majority presented age up to 50 years with a higher prevalence in G2 (p <0.001), without socioeconomic differences and educational level. Conclusion: G1, although younger, had higher dental losses and periodontal changes. Severity difference of HPTP or socioeconomic status does not explain the findings.