Eficácia do método pilates e da suplementação com extrato de camellia sinensis nos marcadores do metabolismo redox e na composição corporal de voluntárias portadoras critérios diagnósticos para síndrome metabólica : ensaio clínico, placebo-controlado e duplo cego

Detalhes bibliográficos
Ano de defesa: 2016
Autor(a) principal: Junges, Silvana lattes
Orientador(a): Gottlieb, Maria Gabriela Valle lattes
Banca de defesa: Não Informado pela instituição
Tipo de documento: Tese
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Pontifícia Universidade Católica do Rio Grande do Sul
Programa de Pós-Graduação: Programa de Pós-Graduação em Gerontologia Biomédica
Departamento: Instituto de Geriatria e Gerontologia
País: Brasil
Palavras-chave em Português:
Área do conhecimento CNPq:
Link de acesso: http://tede2.pucrs.br/tede2/handle/tede/7006
Resumo: Introduction: Metabolic syndrome (MS) is a complex and large epidemiological importance disorder, it is responsible for the increase in cardiovascular mortality, however, little is known about its etiology. Genetic predisposition, poor diet and physical inactivity are among the major cardiovascular risk factors that may contribute to its appearance due to disturbances that these factors cause the cellular redox system. The literature is ample evidence that both the intake of functional foods such as sinensis Cammelia (ECS) as the exercise Pilates can assist in health promotion and have a protective effect against oxidative processes, playing an important role in reducing the risk of MS. Objectives: To evaluate the effectiveness of training with Pilates and supplementation with the extract Cammelia sinensis (ECS) in the modulation of biochemical markers, oxidative, antioxidant capacity and body composition after voluntary menopausal patients with diagnostic criteria for metabolic syndrome. Methods: We conducted a randomized clinical trial, placebo controlled, double-blind, post-menopausal volunteers from the community of Porto Alegre, carrying diagnostic criteria for metabolic syndrome. Were randomized 60 volunteers and divided into 04 arms: Group 1) Pilates + ECS (15 volunteers); group 2) Pilates + Placebo (15 volunteers); group 3) ECS (15 volunteers) and group 4) Placebo (15 volunteers). Intervention groups ECS and ECS + Pilates consumed a capsule with 500mg excipient ECS per day, which could be ingested one hour after the main meal, for 24 consecutive weeks. The placebo group also consumed a placebo capsule with excipient for 24 consecutive weeks. The training with Pilates was performed for 24 weeks for 60 minutes, performed twice a week. The variables were: sociodemographic, body composition and markers of oxidative metabolism (AOPP, FRAP, NOx, IMA). Statistical applied was: to compare averages, analysis of variance (ANOVA) one way, Tukey test were applied. In the case of asymmetry, the Kruskal-Wallis test was used. To adjust for differences in relation to the baseline measurement, the Analysis of Covariance (ANCOVA) complemented by the Bonferroni test were applied. The significance level was 5% (p <0.05). Results: The mean age of the sample was 61.3 ± 6.6 years (range 51-77 years). The mean age did not differ between groups (p = 0.462)., being respectively: Pilates + ECS group (60.5 ± 6.2), Pilates + Placebo group (62.6 ± 6.7), ECS group (59.1 ± 4, 7) and placebo group (62.9 ± 8.0). It was found that the circumference of Pilates + Green Tea groups waist was significantly lower than that of Green Tea and Placebo groups after intervention (p <0.001). Triglyceride levels of Pilates groups + Green Tea and Pilates + Placebo were significantly lower than the placebo group (p = 0.010). Glucose levels (p = 0.041), BMI (p = 0.008) and fat mass + Green Tea Pilates group was significantly lower than in the placebo group (p = 0.013). The means of lean mass in kg of Pilates and Pilates + Green Tea + placebo groups were significantly higher than the group Green Tea and Placebo (<0.001). As the percentage of lean mass from the + Green Tea Pilates group was significantly higher than the groups Green Tea and Placebo, and the percentage of lean mass Pilates + Placebo group was significantly higher only compared to placebo (p = <0.001). Regarding body fat percentage, a + Green Tea Pilates group was significantly lower than the groups Green Tea and Placebo, and the body fat percentage Pilates + Placebo group was significantly lower than the placebo (p = 0.001). There were no statistically significant differences in post-intervention in relation to the redox metabolism markers (p> 0.05). Conclusion: The results suggest that the Pilates method of exercise with and without supplementation with ECS are effective for reducing the means of the waist circumference, triglycerides and glucose, as well as the variables of body composition in postmenopausal women.